Pantoprazole and Colistimethate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pantoprazole (pantoprazole sodium) and Colistimethate (colistimethate sodium). Common drug interactions include myasthenic syndrome among females and septic shock among males.
The phase IV clinical study analyzes what interactions people have when they take Pantoprazole and Colistimethate. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.
What is Pantoprazole?
Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.
What is Colistimethate?
Colistimethate has active ingredients of colistimethate sodium. eHealthMe is studying from 1,502 Colistimethate users. Check the latest studies of Colistimethate.
80 people who take Pantoprazole and Colistimethate together, and have interactions are studied.

What are the common drug interactions of Pantoprazole and Colistimethate, by gender? *:
female:
- Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Cystic fibrosis (disease of the secretary glands)
- Dyspnoea (difficult or laboured respiration)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Chest discomfort
- Hospitalisation
- Pruritus generalised (generalized itching)
- Confusional state
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
male:
- Septic shock (shock due to blood infection)
- Eosinophilia (eosinophil count in the peripheral blood exceeds)
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
- Cystic fibrosis (disease of the secretary glands)
- Electrolyte imbalance
- Forced expiratory volume decreased (decreased lung expired air volume)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hepatitis (inflammation of the liver)
- Hospitalisation
What are the common drug interactions of Pantoprazole and Colistimethate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Hospitalisation
20-29:
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Septic shock (shock due to blood infection)
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Cystic fibrosis (disease of the secretary glands)
- Cystic fibrosis lung (fibrosis with cyst in the lung)
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Pain
- Pulmonary function test decreased
30-39:
- Cardiac arrest
- Cystic fibrosis (disease of the secretary glands)
- Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
- Hospitalisation
- Hypotension (abnormally low blood pressure)
- Myositis (inflammation of the muscles)
- Oedema peripheral (superficial swelling)
- Parainfluenzae virus infection
- Renal impairment (severely reduced kidney function)
- Rib fracture
40-49:
- Pruritus generalised (generalized itching)
- Chest discomfort
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Muscular weakness (muscle weakness)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Antibiotic therapy
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Cough
50-59:
- Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
- Cystic fibrosis (disease of the secretary glands)
- Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
- Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
- Hepatitis (inflammation of the liver)
- Hypokalaemia (low potassium)
- Infusion related reaction
- Paralysis flaccid (abnormal condition characterized by the weakening or the loss of muscle tone)
- Pneumonia
- Pneumonia bacterial (pneumonia associated with bacterial infection)
60+:
- Eosinophilia (eosinophil count in the peripheral blood exceeds)
- Drug ineffective
- Electrolyte imbalance
- Flushing (the warm, red condition of human skin)
- Hot flush (sudden feelings of heat)
- Hypernatraemia (an abnormally high plasma concentration of sodium ions)
- Hypertransaminasaemia
- Hypoxia (low oxygen in tissues)
- Intervertebral disc protrusion (spinal disc protrusion)
- Intestinal haemorrhage (bleeding from intestine)
What are the existing conditions these people have? *
- Cystic Fibrosis (disease of the secretary glands): 36 people, 45.00%
- Pneumonia: 7 people, 8.75%
- Pain: 6 people, 7.50%
- High Blood Pressure: 6 people, 7.50%
- Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 5.00%
- Klebsiella Infection: 4 people, 5.00%
- Cystic Fibrosis Lung (fibrosis with cyst in the lung): 4 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Pantoprazole and Colistimethate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pantoprazole (285,165 reports)
- Colistimethate (1,502 reports)
Browse all drug interactions of Pantoprazole and Colistimethate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pantoprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Colistimethate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pantoprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colistimethate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pantoprazole sodium and colistimethate sodium (the active ingredients of Pantoprazole and Colistimethate, respectively), and Pantoprazole and Colistimethate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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