Paracetamol and Catapres drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol (acetaminophen) and Catapres (clonidine hydrochloride). Common drug interactions include fatigue among females and toxic epidermal necrolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Catapres. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.



On Jul, 26, 2026

49 people who take Paracetamol and Catapres together, and have interactions are studied.

Paracetamol and Catapres drug interactions.

What are the common drug interactions of Paracetamol and Catapres, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Anaemia (lack of blood)
  3. Asthma
  4. Back pain
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Coeliac disease (simple food intolerance)
  7. Constipation
  8. Drug hypersensitivity
  9. Erythema (redness of the skin)
  10. Fluid retention (an abnormal accumulation of fluid in the blood)

male:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Anaemia (lack of blood)
  4. Blood culture positive
  5. Confusional state
  6. Disease recurrence
  7. Gastric haemorrhage (bleeding stomach)
  8. Gastrointestinal pain
  9. Haemodynamic instability (disturbances in the blood movement in our body)
  10. Hepatocellular injury (liver injury)

What are the common drug interactions of Paracetamol and Catapres, by age (0-1 to 60+)? *:

0-1:

  1. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  2. Dissociation
  3. Emotional disorder
  4. Social avoidant behaviour (avoiding social connection a personality disorder)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

2-9:

  1. Gastric haemorrhage (bleeding stomach)

10-19:

  1. Dehydration (dryness resulting from the removal of water)
  2. Fatigue (feeling of tiredness)
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Disturbance in attention
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

  1. Cholecystitis (infection of gallbladder)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)

30-39:

n/a

40-49:

n/a

50-59:

  1. Asthma
  2. Back pain
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Coeliac disease (simple food intolerance)
  5. Constipation
  6. Drug hypersensitivity
  7. Erythema (redness of the skin)
  8. Fatigue (feeling of tiredness)
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Food allergy

60+:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Confusional state
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  6. Venoocclusive liver disease (small veins in the liver are obstructed)
  7. Alanine aminotransferase increased
  8. Blood bilirubin increased
  9. Dilatation intrahepatic duct acquired
  10. Disease recurrence

What are the existing conditions these people have? *

  1. Constipation: 20 people, 40.82%
  2. Sedation: 19 people, 38.78%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 19 people, 38.78%
  4. Depression: 19 people, 38.78%
  5. Fever: 18 people, 36.73%
  6. Diarrhea: 18 people, 36.73%
  7. Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 17 people, 34.69%
  8. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 17 people, 34.69%
  9. Stress And Anxiety: 17 people, 34.69%
  10. Pneumonia: 17 people, 34.69%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and Catapres?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paracetamol and Catapres:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Catapres:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Catapres and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and clonidine hydrochloride (the active ingredients of Paracetamol and Catapres, respectively), and Paracetamol and Catapres (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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