Paracetamol and Nitrolingual drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Paracetamol (acetaminophen) and Nitrolingual (nitroglycerin). Common drug interactions include depression among females and atrial fibrillation among males.
The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Nitrolingual. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.
What is Paracetamol?
Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.
What is Nitrolingual?
Nitrolingual has active ingredients of nitroglycerin. eHealthMe is studying from 2,777 Nitrolingual users. Check the latest studies of Nitrolingual.
79 people who take Paracetamol and Nitrolingual together, and have interactions are studied.

What are the common drug interactions of Paracetamol and Nitrolingual, by gender? *:
female:
- Depression
- Dysphagia (a condition in which swallowing is difficult or painful)
- Erythema (redness of the skin)
- Feeling of body temperature change
- Foot fracture
- Hypoaesthesia (reduced sense of touch or sensation)
- Intervertebral disc protrusion (spinal disc protrusion)
- Irritability
- Lethargy (tiredness)
- Neuropathy peripheral (surface nerve damage)
male:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Febrile neutropenia (fever with reduced white blood cells)
- Chest discomfort
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Disturbance in attention
- Dyspnoea (difficult or laboured respiration)
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Gait disturbance
- Hypertension (high blood pressure)
What are the common drug interactions of Paracetamol and Nitrolingual, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Influenza like illness
- Injection site erythema (redness at injection site)
- Injection site induration
- Injection site reaction
- Loss of consciousness
- Muscle spasms (muscle contraction)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Cardiac disorder
50-59:
- Diabetes mellitus inadequate control
- Diarrhoea
- Haemoglobin decreased
- Hepatitis toxic
- Nausea (feeling of having an urge to vomit)
- Red blood cell count decreased
- Tremor (trembling or shaking movements in one or more parts of your body)
- White blood cell count decreased
- Wound
60+:
- Pneumonia
- Malaise (a feeling of general discomfort or uneasiness)
- Bone pain
- Bradycardia (abnormally slow heart action)
- Contusion (a type of hematoma of tissue in which capillaries)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Disturbance in attention
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
What are the existing conditions these people have? *
- High Blood Pressure: 27 people, 34.18%
- High Blood Cholesterol: 13 people, 16.46%
- Type 2 Diabetes: 12 people, 15.19%
- Chest Pain: 9 people, 11.39%
- Stable Angina (a constant chest pain): 8 people, 10.13%
- Dyspnea (difficult or laboured breathing): 7 people, 8.86%
- Insomnia (sleeplessness): 7 people, 8.86%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 7.59%
- Diabetes: 6 people, 7.59%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 5 people, 6.33%
* Approximation only. Some reports may have incomplete information.
Do you take Paracetamol and Nitrolingual?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Paracetamol (115,650 reports)
- Nitrolingual (2,777 reports)
Browse all drug interactions of Paracetamol and Nitrolingual:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Paracetamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nitrolingual:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paracetamol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitrolingual and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetaminophen and nitroglycerin (the active ingredients of Paracetamol and Nitrolingual, respectively), and Paracetamol and Nitrolingual (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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