Abstral and Magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abstral (fentanyl citrate) and Magnesium (magnesium). Common drug interactions include syncope among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Abstral and Magnesium. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Abstral?

Abstral has active ingredients of fentanyl citrate. eHealthMe is studying from 1,390 Abstral users. Check the latest studies of Abstral.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,145 Magnesium users. Check the latest studies of Magnesium.



On Aug, 11, 2026

59 people who take Abstral and Magnesium together, and have interactions are studied.

Abstral and Magnesium drug interactions.

What are the common drug interactions of Abstral and Magnesium, by gender? *:

female:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Anaemia (lack of blood)
  3. Dehydration (dryness resulting from the removal of water)
  4. Acute hepatic failure
  5. Alanine aminotransferase increased
  6. Ammonia increased
  7. Aspartate aminotransferase increased
  8. Blood bilirubin increased
  9. Colorectal cancer recurrent (colon cancer has returned after the cure)
  10. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)

male:

  1. Diarrhoea
  2. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  3. Abdominal pain upper
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Oedema peripheral (superficial swelling)
  6. Renal impairment (severely reduced kidney function)
  7. Death
  8. Cough
  9. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  10. Febrile neutropenia (fever with reduced white blood cells)

What are the common drug interactions of Abstral and Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  2. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  3. Lymphadenopathy (disease or enlargement of lymph nodes)
  4. Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

  1. Acute hepatic failure
  2. Alanine aminotransferase increased
  3. Ammonia increased
  4. Aspartate aminotransferase increased
  5. Blood bilirubin increased
  6. Colorectal cancer recurrent (colon cancer has returned after the cure)
  7. Death
  8. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  9. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  10. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)

60+:

  1. Diarrhoea
  2. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  3. Anaemia (lack of blood)
  4. Dehydration (dryness resulting from the removal of water)
  5. Abdominal pain upper
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Malignant neoplasm progression (cancer tumour came back)
  8. Oedema peripheral (superficial swelling)
  9. Renal impairment (severely reduced kidney function)
  10. Cough

What are the existing conditions these people have? *

  1. Breakthrough Pain: 14 people, 23.73%
  2. Laxative Supportive Care: 14 people, 23.73%
  3. Fever: 7 people, 11.86%
  4. High Blood Pressure: 7 people, 11.86%
  5. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 11.86%
  6. Abdominal Pain: 6 people, 10.17%
  7. Pain: 6 people, 10.17%
  8. Nausea (feeling of having an urge to vomit): 6 people, 10.17%
  9. Anaemia (lack of blood): 5 people, 8.47%
  10. Migraine (headache): 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Abstral and Magnesium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Abstral and Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Abstral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abstral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate and magnesium (the active ingredients of Abstral and Magnesium, respectively), and Abstral and Magnesium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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