Paracetamol and Rapaflo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol (acetaminophen) and Rapaflo (silodosin). Common drug interactions include dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Paracetamol and Rapaflo. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Rapaflo?

Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.



On Jul, 25, 2026

17 people who take Paracetamol and Rapaflo together, and have interactions are studied.

Paracetamol and Rapaflo drug interactions.

What are the common drug interactions of Paracetamol and Rapaflo, by gender? *:

female:

n/a

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Oxygen saturation decreased
  3. Bacterial infection
  4. Blood potassium increased
  5. Body temperature increased
  6. Bowel movement irregularity
  7. Chills (felling of cold)
  8. Choreoathetosis (involuntary movement randomly from one part to another body part)
  9. Cough
  10. Cystitis (inflammation of the wall of the bladder)

What are the common drug interactions of Paracetamol and Rapaflo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Reversible airways obstruction (reverse of airway obstruction)
  2. Dyspnoea (difficult or laboured respiration)
  3. Body temperature increased
  4. Bowel movement irregularity
  5. Chills (felling of cold)
  6. Choreoathetosis (involuntary movement randomly from one part to another body part)
  7. Cough
  8. Cystitis (inflammation of the wall of the bladder)
  9. Death
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

  1. Prostate Cancer Metastatic: 3 people, 17.65%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 11.76%
  4. Hyperkalemia (damage to or disease of the kidney): 2 people, 11.76%
  5. Mucosal Inflammation (infection of mucous membrane): 1 person, 5.88%
  6. Migraine (headache): 1 person, 5.88%
  7. Drowsiness: 1 person, 5.88%
  8. Breast Cancer: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and Rapaflo?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paracetamol and Rapaflo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rapaflo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rapaflo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and silodosin (the active ingredients of Paracetamol and Rapaflo, respectively), and Paracetamol and Rapaflo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: