Parcopa and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Parcopa (carbidopa; levodopa) and Wellbutrin (bupropion hydrochloride). Common drug interactions include coronary artery occlusion among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Parcopa and Wellbutrin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Parcopa?

Parcopa has active ingredients of carbidopa; levodopa. eHealthMe is studying from 234 Parcopa users. Check the latest studies of Parcopa.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,107 Wellbutrin users. Check the latest studies of Wellbutrin.

On Jul, 28, 2026

11 people who take Parcopa and Wellbutrin together, and have interactions are studied.

Parcopa and Wellbutrin drug interactions.

What are the common drug interactions of Parcopa and Wellbutrin, by gender? *:

female:

Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Coronary artery stenosis (narrowing of coronary artery)
Blood urea increased
Chest pain
Dehydration (dryness resulting from the removal of water)
Electrocardiogram repolarisation abnormality
Fall
Femoral neck fracture (neck of femur bone fracture)
Groin pain
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

male:

Emotional distress
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
Somnolence (a state of near-sleep, a strong desire for sleep)
Pain
Pathological gambling
Decreased interest
Dizziness
Fear
Injection site bruising

What are the common drug interactions of Parcopa and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Emotional distress
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pain
Pathological gambling

50-59:

n/a

60+:

Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Coronary artery stenosis (narrowing of coronary artery)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Blood creatine increased
Blood creatinine increased

What are the existing conditions these people have? *

Parkinson's Disease: 9 people, 81.82%
Insomnia (sleeplessness): 2 people, 18.18%
Sinusitis (inflammation of sinus): 1 person, 9.09%
Pain: 1 person, 9.09%
Jock Itch (fungal infection of the groin and upper thighs): 1 person, 9.09%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 1 person, 9.09%
Allergic Rhinitis: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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