Paricalcitol and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paricalcitol (paricalcitol) and Protonix (pantoprazole sodium). Common drug interactions include normochromic normocytic anaemia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Paricalcitol and Protonix. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Paricalcitol?

Paricalcitol has active ingredients of paricalcitol. eHealthMe is studying from 1,278 Paricalcitol users. Check the latest studies of Paricalcitol.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 12, 2026

58 people who take Paricalcitol and Protonix together, and have interactions are studied.

Paricalcitol and Protonix drug interactions.

What are the common drug interactions of Paricalcitol and Protonix, by gender? *:

female:

Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Pleural effusion (water on the lungs)
Therapeutic response decreased (less preventive response)
Thymoma (a tumour originating from the epithelial cells of the thymus)
Cardiac failure congestive
Death
Dyspnoea (difficult or laboured respiration)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Abdominal discomfort
Hypotension (abnormally low blood pressure)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Unresponsive to stimuli
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Paricalcitol and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Asthenia (weakness)
Blood pressure systolic increased
Decreased appetite
Fatigue (feeling of tiredness)
Haemoglobin decreased
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pain

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Arthralgia (joint pain)
Asthenia (weakness)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cough
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)

50-59:

Hypertension (high blood pressure)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypokinesia (decreased bodily movement)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Joint stiffness
Lymphoedema (localized fluid retention and tissue swelling)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Muscle spasms (muscle contraction)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Back pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Gastrointestinal arteriovenous malformation (malformation of arteries and veins in gastrointestinal tract)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypertension (high blood pressure)
Lipoma (a growth of fatty tissue that slowly develops just under your skin)

What are the existing conditions these people have? *

High Blood Cholesterol: 21 people, 36.21%
High Blood Pressure: 15 people, 25.86%
Pain: 14 people, 24.14%
Nephrogenic Anaemia (anaemia due to kidney disease): 10 people, 17.24%
Gout (uric acid crystals building up in the body): 10 people, 17.24%
Renal Disorder (kidney disease): 9 people, 15.52%
Infection: 8 people, 13.79%
Muscle Spasms (muscle contraction): 7 people, 12.07%
Fluid Retention (an abnormal accumulation of fluid in the blood): 7 people, 12.07%
Indigestion: 7 people, 12.07%

* Approximation only. Some reports may have incomplete information.

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