Paroxetine and Ofev drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paroxetine (paroxetine hydrochloride) and Ofev (nintedanib esylate). Common drug interactions include cerebrovascular accident among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Paroxetine and Ofev. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.

On Aug, 01, 2026

39 people who take Paroxetine and Ofev together, and have interactions are studied.

What are the common drug interactions of Paroxetine and Ofev, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dysgeusia (disorder of the sense of taste)
Fall
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Abdominal distension
Contusion (a type of hematoma of tissue in which capillaries)
Cow's milk intolerance (milk allergy)
Feeling cold
Hot flush (sudden feelings of heat)
Pruritus (severe itching of the skin)

male:

Diarrhoea
Arthralgia (joint pain)
Joint range of motion decreased (disease of joint movement)
Joint swelling
Neutropenia (an abnormally low number of neutrophils)
Pulmonary function test decreased
Abdominal discomfort
Arrhythmia (irregular heartbeat)
Cardiomegaly (increased size of heart than normal)
Cerebral atrophy (decrement in size of brain)

What are the common drug interactions of Paroxetine and Ofev, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Nausea (feeling of having an urge to vomit)
Decreased appetite
Malaise (a feeling of general discomfort or uneasiness)
Abdominal discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea exertional (breathlessness or shortness of breath)
Ageusia (loss of taste functions of the tongue)
Back injury
Blood iron decreased
Idiopathic pulmonary fibrosis (chronic lung disease)

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 32 people, 82.05%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 17.95%
High Blood Pressure: 3 people, 7.69%
Thyroid Diseases: 2 people, 5.13%
Lung Disorder (lung disease): 2 people, 5.13%
Interstitial Lung Disease: 2 people, 5.13%
Gout (uric acid crystals building up in the body): 2 people, 5.13%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.13%
Cardiac Failure: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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