Paroxetine and Psyllium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paroxetine (paroxetine hydrochloride) and Psyllium (blond psyllium). Common drug interactions include poor peripheral circulation among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Paroxetine and Psyllium. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

On Jul, 20, 2026

42 people who take Paroxetine and Psyllium together, and have interactions are studied.

Paroxetine and Psyllium drug interactions.

What are the common drug interactions of Paroxetine and Psyllium, by gender? *:

female:

Poor peripheral circulation
Postoperative wound infection
Vein disorder
Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
Muscle tightness
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)

male:

Pain
Asthenia (weakness)
Appetite disorder (abnormal eating habits)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Balance disorder
Bipolar disorder (mood disorder)
Bone pain
Cataract (clouding of the lens inside the eye)
Concussion (short loss of normal brain function in response to a head injury)
Dizziness

What are the common drug interactions of Paroxetine and Psyllium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Emotional distress
Chronic kidney disease
Decreased activity
Diarrhoea
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

40-49:

Feeling hot
Hyperhidrosis (abnormally increased sweating)

50-59:

Renal impairment (severely reduced kidney function)
Chronic kidney disease
Renal failure (kidney dysfunction)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Post-traumatic stress disorder
Wound
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Asthenia (weakness)
Muscle spasms (muscle contraction)
Cataract (clouding of the lens inside the eye)
Concussion (short loss of normal brain function in response to a head injury)
Diarrhoea
Dizziness
Extraocular muscle paresis (nerve paralysis outside of eye tissue)
Faecaloma (hard mass of fecal matter)
Faeces discoloured
Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

Pain: 13 people, 30.95%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 19.05%
High Blood Cholesterol: 7 people, 16.67%
Nausea (feeling of having an urge to vomit): 6 people, 14.29%
High Blood Pressure: 6 people, 14.29%
Depression: 6 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 11.90%
Oedema (fluid collection in tissue): 5 people, 11.90%
Infection: 5 people, 11.90%

* Approximation only. Some reports may have incomplete information.

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