Patanol and Clopra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Patanol (olopatadine hydrochloride) and Clopra (metoclopramide hydrochloride). Common drug interactions include extrapyramidal disorder among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Patanol and Clopra. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Patanol?

Patanol has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,339 Patanol users. Check the latest studies of Patanol.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

On Jul, 20, 2026

58 people who take Patanol and Clopra together, and have interactions are studied.

What are the common drug interactions of Patanol and Clopra, by gender? *:

female:

Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Tardive dyskinesia (a disorder that involves involuntary movements)
Fatigue (feeling of tiredness)
Headache (pain in head)
Vomiting
Mitral valve incompetence (inefficient heart valve)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Arthralgia (joint pain)
Dizziness

male:

Asthenia (weakness)
Chronic kidney disease
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Emotional distress
Fluid overload (too much fluid in the blood)
Gastritis (inflammation of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Leukocytosis (increased white blood cells)
Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Patanol and Clopra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Pain
Ankle fracture
Anxiety
Bone density decreased
Bone loss
Chronic kidney disease
Ligament rupture (tear in ligament)
Lower limb fracture

40-49:

Pain
Chest pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Pulmonary embolism (blockage of the main artery of the lung)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety

50-59:

Insomnia (sleeplessness)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Impaired gastric emptying
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Asthenia (weakness)
Ascites (accumulation of fluid in the abdominal cavity)
Chills (felling of cold)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Emotional disorder
Fluid overload (too much fluid in the blood)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 27.59%
Pain: 13 people, 22.41%
Hypersensitivity: 9 people, 15.52%
High Blood Pressure: 8 people, 13.79%
Asthma: 8 people, 13.79%
Nausea (feeling of having an urge to vomit): 8 people, 13.79%
Diabetes: 8 people, 13.79%
Constipation: 8 people, 13.79%
High Blood Cholesterol: 7 people, 12.07%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 12.07%

* Approximation only. Some reports may have incomplete information.

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