Paxil and Avandaryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil (paroxetine hydrochloride) and Avandaryl (glimepiride; rosiglitazone maleate). Common drug interactions include myocardial infarction among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil and Avandaryl. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Avandaryl?

Avandaryl has active ingredients of glimepiride; rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 2,660 Avandaryl users. Check the latest studies of Avandaryl.

On Jul, 13, 2026

21 people who take Paxil and Avandaryl together, and have interactions are studied.

What are the common drug interactions of Paxil and Avandaryl, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cardiac failure congestive
Abdominal pain
Headache (pain in head)
Oropharyngeal pain
Thrombosis (formation of a blood clot inside a blood vessel)
Blood cholesterol increased
Chest pain
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal hernia
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal mediastinitis (an infection with staphylococcus bacteria of the tissues in the mid-chest)
Tricuspid valve incompetence (inefficient heart valve)
Wound infection
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation

What are the common drug interactions of Paxil and Avandaryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Thrombosis (formation of a blood clot inside a blood vessel)
Blood cholesterol increased
Blood triglycerides increased
Borderline personality disorder
Diabetic nephropathy (diabetic kidney disease)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dizziness
Headache (pain in head)
Hot flush (sudden feelings of heat)

40-49:

Abdominal pain
Oropharyngeal pain
Chest pain
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Neck pain
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Road traffic accident
Tenderness (pain or discomfort when an affected area is touched)

50-59:

Pleural effusion (water on the lungs)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pulmonary valve stenosis (heart valve disorder in which outflow of blood from the right ventricle of the heart is obstructed at the level of the pulmonic valve)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal mediastinitis (an infection with staphylococcus bacteria of the tissues in the mid-chest)
Tricuspid valve incompetence (inefficient heart valve)
Wound infection
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arteriosclerosis (thickening and hardening of arteries)

60+:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Constipation

What are the existing conditions these people have? *

Sleep Disorder: 2 people, 9.52%
Bipolar Disorder (mood disorder): 2 people, 9.52%
Adenocarcinoma Pancreas (cancer of pancreas): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and Avandaryl?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously