Paxil and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil (paroxetine hydrochloride) and Memantine (memantine). Common drug interactions include balance disorder among females and prostatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil and Memantine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.



On Jul, 09, 2026

21 people who take Paxil and Memantine together, and have interactions are studied.

Paxil and Memantine drug interactions.

What are the common drug interactions of Paxil and Memantine, by gender? *:

female:

  1. Balance disorder
  2. Back pain
  3. Cataract (clouding of the lens inside the eye)
  4. Depressed level of consciousness
  5. Hallucination (an experience involving the perception of something not present)
  6. Hyperglycaemia (high blood sugar)
  7. Interstitial lung disease
  8. Spinal osteoarthritis (joint cartilage loss in spine)
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Vision blurred

male:

  1. Prostatitis (inflammation of the prostate gland)
  2. Weight decreased
  3. Leukocytosis (increased white blood cells)
  4. Malignant melanoma (skin cancer rises from melancytes)
  5. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  6. Post procedural haematuria (post procedural blood in urine)
  7. Asthenia (weakness)
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Confusional state
  10. Death

What are the common drug interactions of Paxil and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Spinal osteoarthritis (joint cartilage loss in spine)
  2. Vision blurred
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Back disorder
  5. Back pain
  6. Blood glucose decreased
  7. Blood pressure orthostatic decreased
  8. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  9. Confusional state
  10. Depressed level of consciousness

60+:

  1. Prostatitis (inflammation of the prostate gland)
  2. Weight decreased
  3. Haemorrhagic transformation stroke (haemorrhages develop inside areas of ischemia)
  4. International normalised ratio increased
  5. Leukocytosis (increased white blood cells)
  6. Malignant melanoma (skin cancer rises from melancytes)
  7. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  8. Post procedural haematuria (post procedural blood in urine)
  9. Asthenia (weakness)
  10. Back pain

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 4 people, 19.05%
  2. Ureteral Disorder: 3 people, 14.29%
  3. Renal Disorder (kidney disease): 3 people, 14.29%
  4. Memory Loss: 3 people, 14.29%
  5. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 14.29%
  6. Stress And Anxiety: 2 people, 9.52%
  7. Pancreatic Carcinoma (pancreatic cancer): 2 people, 9.52%
  8. Hypersensitivity: 2 people, 9.52%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 9.52%
  10. High Blood Pressure: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and Memantine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paxil and Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Memantine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride and memantine (the active ingredients of Paxil and Memantine, respectively), and Paxil and Memantine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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