Paxil and Nardil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil (paroxetine hydrochloride) and Nardil (phenelzine sulfate). Common drug interactions include withdrawal syndrome among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil and Nardil. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Nardil?

Nardil has active ingredients of phenelzine sulfate. It is often used in depression. eHealthMe is studying from 2,327 Nardil users. Check the latest studies of Nardil.

On Jul, 13, 2026

35 people who take Paxil and Nardil together, and have interactions are studied.

What are the common drug interactions of Paxil and Nardil, by gender? *:

female:

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Ataxia (loss of full control of bodily movements)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Joint swelling
Muscle contractions involuntary (uncontrolled muscle contraction)
Muscle spasms (muscle contraction)
Drug ineffective
Thrombosis (formation of a blood clot inside a blood vessel)
Oedema peripheral (superficial swelling)
Drug hypersensitivity

male:

Drug ineffective
Drug dependence
Pain
Rebound effect (take-back effect)
Sleep disorder
Stress symptoms
Tremor (trembling or shaking movements in one or more parts of your body)
Suicidal ideation
Adjustment disorder
Aggression

What are the common drug interactions of Paxil and Nardil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug dependence
Headache (pain in head)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Neck pain
Pain in limb
Rebound effect (take-back effect)
Sleep disorder
Stress symptoms
Insomnia (sleeplessness)
Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

Ataxia (loss of full control of bodily movements)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Muscle contractions involuntary (uncontrolled muscle contraction)
Muscle spasms (muscle contraction)

40-49:

n/a

50-59:

Nervousness
Weakness
Balance disorder
Drug hypersensitivity
Feeling jittery
Obsessive thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry)
Tinnitus (a ringing in the ears)
Weight decreased
Blood pressure increased
Constipation

60+:

Drug ineffective
Oedema peripheral (superficial swelling)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypersensitivity
Hypertensive crisis
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Suicidal ideation
Vomiting

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 22.86%
Sleep Disorder: 8 people, 22.86%
Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 14.29%
Panic Disorder: 3 people, 8.57%
Precancerous Cells Present: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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