Paxil and Timoptic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil (paroxetine hydrochloride) and Timoptic (timolol maleate). Common drug interactions include cyanosis among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil and Timoptic. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Timoptic?

Timoptic has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 4,247 Timoptic users. Check the latest studies of Timoptic.

On Jul, 18, 2026

47 people who take Paxil and Timoptic together, and have interactions are studied.

What are the common drug interactions of Paxil and Timoptic, by gender? *:

female:

Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dehydration (dryness resulting from the removal of water)
Depressed mood
Diabetic complication
Diarrhoea
Difficulty in micturition (difficulty to urinate)
Difficulty in walking
Disease recurrence
Drug effect decreased
Drug ineffective

male:

Cardiac disorder
Circulatory collapse
Anosmia (partial or complete loss of the sense of smell)
Arrhythmia (irregular heartbeat)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular disorder (disease of brain)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Constipation
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

What are the common drug interactions of Paxil and Timoptic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood calcium decreased
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Proteinuria (presence of protein in the urine)
Renal impairment (severely reduced kidney function)

40-49:

Cardiac disorder
Circulatory collapse
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Sick sinus syndrome (a collection of heart rhythm disorders)
Type 2 diabetes mellitus
Arthropathy
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Neuropathy peripheral (surface nerve damage)
Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

Dyspnoea exertional (breathlessness or shortness of breath)
Ear disorder
Fatigue (feeling of tiredness)
Fungal infection
Gastrointestinal pain
Glycosuria (excretion of glucose into the urine)
Glycosylated haemoglobin increased
Groin abscess (pus in groin)
Herpes simplex (herpes simplex is a common viral infection)
Hip arthroplasty

60+:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Sedation
Hypertension (high blood pressure)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Multiple myeloma (cancer of the plasma cells)
Pulmonary embolism (blockage of the main artery of the lung)
Renal failure (kidney dysfunction)
Abdominal pain
Abnormal behaviour
Ageusia (loss of taste functions of the tongue)

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 12.77%
Nervousness: 6 people, 12.77%
Insomnia (sleeplessness): 6 people, 12.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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