Paxil and Trimox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paxil (paroxetine hydrochloride) and Trimox (amoxicillin). Common drug interactions include drug ineffective among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Paxil and Trimox. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Trimox?

Trimox has active ingredients of amoxicillin. eHealthMe is studying from 932 Trimox users. Check the latest studies of Trimox.



On Jul, 20, 2026

100 people who take Paxil and Trimox together, and have interactions are studied.

Paxil and Trimox drug interactions.

What are the common drug interactions of Paxil and Trimox, by gender? *:

female:

  1. Drug ineffective
  2. Headache (pain in head)
  3. Dyspnoea (difficult or laboured respiration)
  4. Asthenia (weakness)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Nausea (feeling of having an urge to vomit)
  7. Anaemia macrocytic (a macrocytic class of anaemia)
  8. Carotid artery disease
  9. Compression fracture (fracture due to pressure caused by injury)
  10. Hypercholesterolaemia (high levels of cholesterol in the blood)

male:

  1. Fatigue (feeling of tiredness)
  2. Cholecystitis (infection of gallbladder)
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Back pain
  5. Blood pressure increased
  6. Bone disorder
  7. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  8. Cardiac failure congestive
  9. Cataract (clouding of the lens inside the eye)
  10. Cellulitis (infection under the skin)

What are the common drug interactions of Paxil and Trimox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abnormal behaviour
  2. Hypomania (a mild form of mania, marked by elation and hyperactivity)
  3. Insomnia (sleeplessness)
  4. Overdose
  5. Restlessness (not able to rest)
  6. Suicidal ideation
  7. Suicide attempt

20-29:

  1. Completed suicide (act of taking one's own life)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Alcohol poisoning
  4. Fall
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Drug ineffective
  7. Feeling cold
  8. Laceration (tearing of soft body tissue)
  9. Nightmare (unpleasant dream)
  10. Type 2 diabetes mellitus

30-39:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Chest pain
  3. Alopecia (absence of hair from areas of the body)
  4. Anaemia macrocytic (a macrocytic class of anaemia)
  5. Asthenia (weakness)
  6. Blood triglycerides increased
  7. Carotid artery disease
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Compression fracture (fracture due to pressure caused by injury)
  10. Dyspnoea (difficult or laboured respiration)

40-49:

  1. Asthenia (weakness)
  2. Dizziness
  3. Dyspnoea (difficult or laboured respiration)
  4. Hypertension (high blood pressure)
  5. Aeromona infection (infection caused by bacteria aeromona)
  6. Anaemia (lack of blood)
  7. Arteriovenous fistula occlusion
  8. Atelectasis (partial or complete collapse of the lung)
  9. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  10. Back pain

50-59:

  1. Hepatocellular damage (liver damage)
  2. High density lipoprotein decreased
  3. Hypocholesterolaemia (presence of abnormally small amounts of cholesterol in the circulating blood)
  4. Impaired gastric emptying
  5. Ingrowing nail
  6. Lacrimation increased
  7. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Pain in limb
  10. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

60+:

  1. Chest pain
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Oesophagitis (inflammation of oesophagus)
  4. Ulcer
  5. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  6. Abdominal pain
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  9. Appetite disorder (abnormal eating habits)
  10. Arteriosclerosis (thickening and hardening of arteries)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 20.00%
  2. Multiple Myeloma (cancer of the plasma cells): 14 people, 14.00%
  3. Infection: 14 people, 14.00%
  4. Pain: 13 people, 13.00%
  5. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 9.00%
  6. High Blood Cholesterol: 8 people, 8.00%
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 8 people, 8.00%
  8. High Blood Pressure: 7 people, 7.00%
  9. Asthma: 6 people, 6.00%
  10. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 5 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and Trimox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Paxil and Trimox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trimox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trimox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride and amoxicillin (the active ingredients of Paxil and Trimox, respectively), and Paxil and Trimox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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