Pegasys and Cozaar drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pegasys (peginterferon alfa 2a) and Cozaar (losartan potassium). Common drug interactions include acute respiratory failure among females and platelet count decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Pegasys and Cozaar. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.
What is Pegasys?
Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.
What is Cozaar?
Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.
93 people who take Pegasys and Cozaar together, and have interactions are studied.

What are the common drug interactions of Pegasys and Cozaar, by gender? *:
female:
- Acute respiratory failure
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood sodium decreased
- Brain natriuretic peptide increased
- Cardiac arrest
- Cough
- Dry skin
male:
- Platelet count decreased
- Viith nerve paralysis
- Pyrexia (fever)
- Anaemia (lack of blood)
- Acute respiratory failure
- Ascites (accumulation of fluid in the abdominal cavity)
- Blood glucose increased
- Dyspnoea (difficult or laboured respiration)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Incoherent (talking in a confused and unclear way)
What are the common drug interactions of Pegasys and Cozaar, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Asthma
- Dizziness
- Haemorrhage (bleeding)
- Platelet count decreased
- Retching (strong involuntary effort to vomit)
- Subdural haematoma (blood collects between the skull and the surface of the brain)
50-59:
- Platelet count decreased
- Haemoglobin decreased
- Hepatic steatosis (fatty liver disease)
- Vomiting
- Decreased appetite
- Hot flush (sudden feelings of heat)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Oedema peripheral (superficial swelling)
- Pyrexia (fever)
- Rash
60+:
- Fatigue (feeling of tiredness)
- Decreased appetite
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Incoherent (talking in a confused and unclear way)
- Neutropenia (an abnormally low number of neutrophils)
- Pallor
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Personality change
What are the existing conditions these people have? *
- Diabetes: 8 people, 8.60%
* Approximation only. Some reports may have incomplete information.
Do you take Pegasys and Cozaar?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Pegasys and Cozaar:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pegasys:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cozaar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pegasys and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cozaar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on peginterferon alfa 2a and losartan potassium (the active ingredients of Pegasys and Cozaar, respectively), and Pegasys and Cozaar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Drug interactions of Avastin and Dexamethasone - 14 seconds ago
- Asacol vs. Folic Acid, side effect and effectiveness comparison - 16 seconds ago
- Drug interactions of Norvasc and Cytoxan - 20 seconds ago
- Could Lantus cause Uterine Polyp? - 30 seconds ago
- Could Evista cause Hemiparesis? - 35 seconds ago
- Could Vicodin Hp cause Death? - 37 seconds ago
- Could Evista cause Gastrointestinal Tract Adenoma? - 38 seconds ago
- Could Vesicare cause Blood Disorder? - 48 seconds ago
- Could Blincyto cause Cardiogenic Shock? - 59 seconds ago
- Drug interactions of Suboxone and Prilosec - a minute ago