Asacol vs. Folic acid: side effect and effectiveness comparison (a real world drug study)
Summary:
We compare the side effects and drug effectiveness of Asacol and Folic acid. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 258,162 people who take Asacol and Folic acid, and is updated regularly.
What is Asacol?
Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.
What is Folic acid?
Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.
258,162 people who take Asacol and Folic acid are studied.

Drugs being compared in this study:
- Folic Acid (folic acid)
- Asacol (mesalamine)
Most common side effects of the drugs, overall:
Most common side effects of the drugs, in long term (1+ years) use:
Drug effectiveness:
Asacol:
- not at all: 3.42 %
- somewhat: 18.29 %
- moderate: 32.61 %
- high: 28.56 %
- very high: 17.12 %
Folic Acid:
- not at all: 3.99 %
- somewhat: 19.1 %
- moderate: 34.81 %
- high: 29.96 %
- very high: 12.15 %
Want to compare Asacol with Folic acid?
- Personalize this study to your gender and age (0-99+)How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Related studies
Alternative drugs to, pros and cons of:
- Asacol (19,900 reports)
- Folic acid (162,499 reports)
Browse all side effects of Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Folic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study is based on mesalamine and folic acid (the active ingredients of Asacol and Folic acid, respectively). Other drugs that have the same active ingredients (e.g. generic drugs or brand names) are also considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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