Peginterferon and Seroquel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Peginterferon (peginterferon alfa-2a; ribavirin) and Seroquel (quetiapine fumarate). Common drug interactions include haemoglobin decreased among females and white blood cell count decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Peginterferon and Seroquel. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.
What is Peginterferon?
Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
54 people who take Peginterferon and Seroquel together, and have interactions are studied.

What are the common drug interactions of Peginterferon and Seroquel, by gender? *:
female:
- Haemoglobin decreased
- Hypertension (high blood pressure)
- Hyperuricaemia (level of uric acid in the blood that is abnormally high)
- Injection site mass
- Pancreatitis acute (sudden inflammation of pancreas)
- Anal pruritus (anal itching)
- Anorectal discomfort
- Decreased appetite
- Dyspnoea (difficult or laboured respiration)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
male:
- White blood cell count decreased
- Anaemia (lack of blood)
- Hyperglycaemia (high blood sugar)
- Mania (a state of abnormally elevated or irritable mood)
- Neuropathy peripheral (surface nerve damage)
- Restless legs syndrome (a powerful urge to move your legs)
- Suicidal ideation
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Weight increased
What are the common drug interactions of Peginterferon and Seroquel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dehydration (dryness resulting from the removal of water)
- Renal failure acute (rapid kidney dysfunction)
- Diarrhoea
- Post-traumatic stress disorder
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Renal impairment (severely reduced kidney function)
- Dizziness postural
- Haemoglobin decreased
- Hypertension (high blood pressure)
- Hyperuricaemia (level of uric acid in the blood that is abnormally high)
40-49:
- Epistaxis (bleed from the nose)
- Abnormal sleep-related event
- Anger
- Hyperglycaemia (high blood sugar)
- Mania (a state of abnormally elevated or irritable mood)
- Neuropathy peripheral (surface nerve damage)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Restless legs syndrome (a powerful urge to move your legs)
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
50-59:
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- White blood cell count decreased
- Death
- Pain
- Platelet count decreased
- Unresponsive to stimuli
- Anaemia (lack of blood)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Pancreatitis acute (sudden inflammation of pancreas)
- Decreased appetite
60+:
- Anaemia (lack of blood)
- Fatigue (feeling of tiredness)
- Increased appetite
- Malaise (a feeling of general discomfort or uneasiness)
- Restlessness (not able to rest)
- Sleep disorder
- Therapeutic response unexpected
- Underweight
- Activities of daily living impaired
- Dry mouth
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 14 people, 25.93%
- Depression: 14 people, 25.93%
- High Blood Pressure: 8 people, 14.81%
- Sleep Disorder: 6 people, 11.11%
- Stress And Anxiety: 4 people, 7.41%
- Iron Deficiency Anaemia: 4 people, 7.41%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 7.41%
- Nausea (feeling of having an urge to vomit): 3 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Peginterferon and Seroquel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Peginterferon (13,778 reports)
- Seroquel (120,285 reports)
Browse all drug interactions of Peginterferon and Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Peginterferon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Peginterferon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on peginterferon alfa-2a; ribavirin and quetiapine fumarate (the active ingredients of Peginterferon and Seroquel, respectively), and Peginterferon and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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