Penicillin and Repatha drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Penicillin (penicillin g potassium) and Repatha (evolocumab). Common drug interactions include urinary tract infection among females and hypokalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Penicillin and Repatha. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Penicillin?

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. eHealthMe is studying from 8,567 Penicillin users. Check the latest studies of Penicillin.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.



On Jul, 10, 2026

12 people who take Penicillin and Repatha together, and have interactions are studied.

Penicillin and Repatha drug interactions.

What are the common drug interactions of Penicillin and Repatha, by gender? *:

female:

  1. Urinary tract infection
  2. Vomiting
  3. Weight decreased
  4. Gait disturbance
  5. Femur fracture
  6. Herpes zoster
  7. Hip fracture
  8. Migraine (headache)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Injury

male:

  1. Hypokalaemia (low potassium)
  2. Anaemia (lack of blood)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
  5. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  6. Intervertebral disc degeneration (spinal disc degeneration)
  7. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  8. Osteonecrosis (death of bone)
  9. Pain
  10. Phlebolith (small local, usually rounded, calcification within a vein)

What are the common drug interactions of Penicillin and Repatha, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
  3. Urticaria (rash of round, red welts on the skin that itch intensely)
  4. Hypokalaemia (low potassium)
  5. Anaemia (lack of blood)
  6. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  7. Back pain
  8. Blood creatinine increased
  9. Bone density decreased
  10. Chronic kidney disease

60+:

  1. Gait disturbance
  2. Femur fracture
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Cystitis (inflammation of the wall of the bladder)
  6. Depressed mood
  7. Diarrhoea
  8. Dizziness postural
  9. Dry skin
  10. Ear disorder

What are the existing conditions these people have? *

  1. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 25.00%
  2. Atherosclerosis (disorder of the arteries): 3 people, 25.00%
  3. Hiv Infection: 2 people, 16.67%
  4. Skin Discoloration: 1 person, 8.33%
  5. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 8.33%
  6. Peripheral Swelling: 1 person, 8.33%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
  8. Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 8.33%
  9. Injury: 1 person, 8.33%
  10. Drowsiness: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Penicillin and Repatha?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Penicillin and Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Penicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Penicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repatha and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on penicillin g potassium and evolocumab (the active ingredients of Penicillin and Repatha, respectively), and Penicillin and Repatha (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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