Zantac and Nasal polyps - a phase IV clinical study of FDA data

Summary:

Nasal polyps is reported as a side effect among people who take Zantac (ranitidine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Vitamin D3, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Nasal polyps when taking Zantac. It is created by eHealthMe based on reports of 432,014 people who have side effects when taking Zantac from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Nasal polyps?

Nasal polyps (masses that develop in the lining of the nose) is found to be associated with 391 drugs and 376 conditions by eHealthMe. Check the latest studies of Nasal polyps.



On Jul, 10, 2026

432,014 people reported to have side effects when taking Zantac.
Among them, 18 people (0.0%) have Nasal polyps.

Could Zantac cause Nasal polyps?

Among these 18 people:

How long have people been on Zantac when they have Nasal polyps? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Nasal polyps when taking Zantac? *

  • female: 70.59 %
  • male: 29.41 %

What is the age of people who have Nasal polyps when taking Zantac? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 25.0 %
  • 20-29: 6.25 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 31.25 %
  • 60+: 37.5 %

What are other drugs people take besides Zantac? *

  1. Singulair: 5 people, 27.78%
  2. Vitamin D3: 5 people, 27.78%
  3. Zyrtec: 4 people, 22.22%
  4. Fluticasone Propionate: 4 people, 22.22%
  5. Nexium: 4 people, 22.22%
  6. Modafinil: 4 people, 22.22%
  7. Metoprolol Succinate: 4 people, 22.22%
  8. Lidocaine: 4 people, 22.22%
  9. Hydrochlorothiazide: 4 people, 22.22%
  10. Heparin: 4 people, 22.22%

What are other side effects people have besides Nasal polyps? *

  1. Dyspnea Exertional: 9 people, 50.00%
  2. Sinusitis (inflammation of sinus): 6 people, 33.33%
  3. Headache (pain in head): 5 people, 27.78%
  4. Nausea (feeling of having an urge to vomit): 5 people, 27.78%
  5. Back Pain: 5 people, 27.78%
  6. Chest Pain: 5 people, 27.78%
  7. Swelling: 5 people, 27.78%
  8. Abdominal Discomfort: 4 people, 22.22%
  9. Meningitis Aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed): 4 people, 22.22%
  10. Ear Haemorrhage (bleeding from ear): 4 people, 22.22%

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 4 people, 22.22%
  2. Cystic Fibrosis (disease of the secretary glands): 4 people, 22.22%
  3. Heart Attack: 3 people, 16.67%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 16.67%
  5. Birth Control: 2 people, 11.11%
  6. Sinusitis (inflammation of sinus): 1 person, 5.56%
  7. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 5.56%
  8. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.56%
  9. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 5.56%
  10. Migraine (headache): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac and have Nasal polyps?

- Check whether Nasal polyps is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zantac:

Nasal polyps treatments and more:

How severe was Nasal polyps and when was it recovered:

Expand to all the drugs that have ingredients of ranitidine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zantac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nasal polyps:

Browse all the conditions that are associated with Nasal polyps:


How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac) and Zantac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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