Penlac and Lyrica drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Penlac (ciclopirox) and Lyrica (pregabalin). Common drug interactions include arthralgia among females and brachial plexus injury among males.

The phase IV clinical study analyzes what interactions people have when they take Penlac and Lyrica. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Penlac?

Penlac has active ingredients of ciclopirox. eHealthMe is studying from 492 Penlac users. Check the latest studies of Penlac.

What is Lyrica?

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 261,646 Lyrica users. Check the latest studies of Lyrica.

On May, 29, 2026

76 people who take Penlac and Lyrica together, and have interactions are studied.

What are the common drug interactions of Penlac and Lyrica, by gender? *:

female:

Arthralgia (joint pain)
Drug ineffective
Tremor (trembling or shaking movements in one or more parts of your body)
Vertigo
Fall
Peripheral swelling
Upper limb fracture
Neuropathy peripheral (surface nerve damage)
Hypoaesthesia (reduced sense of touch or sensation)
Gait disturbance

male:

Brachial plexus injury (brachial plexus injuries, are caused by damage to those nerves network that conducts signals from the spinal cord)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Migraine (headache)
Multiple injuries
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Respiratory tract infection
Thyroid disorder (thyroid diseases)
Urinary tract infection

What are the common drug interactions of Penlac and Lyrica, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Brachial plexus injury (brachial plexus injuries, are caused by damage to those nerves network that conducts signals from the spinal cord)
Migraine (headache)
Thyroid disorder (thyroid diseases)

30-39:

Cardiac disorder
Pancreatic disorder
Renal disorder (kidney disease)

40-49:

Dehydration (dryness resulting from the removal of water)
Dizziness
Erythrasma (skin disease that causes brown, scaly skin patches)
Injection site extravasation (flow of (blood or lymph) from injection site)
Injection site nerve damage
Injection site pain
Injection site rash
Limb discomfort (discomfort in leg)
Pain in extremity
Infusion site haemorrhage (bleeding from infusion site)

50-59:

Device related infection
Diplopia (double vision)
Dizziness
Dry eye (lack of adequate tears)
Dry mouth
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Eye irritation
Facial pain
Fatigue (feeling of tiredness)

60+:

Arthralgia (joint pain)
Pain in extremity
Gait disturbance
Nervousness
Blindness
Confusional state
Eye pain
Head injury
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the existing conditions these people have? *

Pain: 32 people, 42.11%
Stress And Anxiety: 21 people, 27.63%
Nausea (feeling of having an urge to vomit): 17 people, 22.37%
Joint Pain: 15 people, 19.74%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 13 people, 17.11%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 13 people, 17.11%
Restless Leg Syndrome (a powerful urge to move your legs): 12 people, 15.79%
Abdominal Pain: 12 people, 15.79%
Bipolar Disorder (mood disorder): 12 people, 15.79%
Neuropathy Peripheral (surface nerve damage): 12 people, 15.79%

* Approximation only. Some reports may have incomplete information.

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