Pentasa and Yasmin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentasa (mesalamine) and Yasmin (drospirenone; ethinyl estradiol). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Pentasa and Yasmin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.

What is Yasmin?

Yasmin has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 48,855 Yasmin users. Check the latest studies of Yasmin.



On Jul, 26, 2026

44 people who take Pentasa and Yasmin together, and have interactions are studied.

Pentasa and Yasmin drug interactions.

What are the common drug interactions of Pentasa and Yasmin, by gender? *:

female:

  1. Pain
  2. Injury
  3. Diarrhoea
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting
  6. Cholecystitis chronic (long lasting infection of gallbladder)
  7. Abdominal pain
  8. Cholecystitis (infection of gallbladder)
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

n/a

What are the common drug interactions of Pentasa and Yasmin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Exercise tolerance decreased
  2. Palpitations (feelings or sensations that your heart is pounding or racing)
  3. Pulmonary embolism (blockage of the main artery of the lung)
  4. Pulmonary veno-occlusive disease (obstructive disease of the pulmonary veins)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Back pain
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Deformity (disfigurement)
  10. Gallbladder disorder

20-29:

  1. Injury
  2. Pain
  3. Anxiety
  4. Emotional distress
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  9. Dyspnoea (difficult or laboured respiration)
  10. Abdominal pain upper

30-39:

  1. Injury
  2. Road traffic accident
  3. Anxiety
  4. Nausea (feeling of having an urge to vomit)
  5. Pyrexia (fever)
  6. Vomiting
  7. Abdominal pain upper
  8. Cholecystitis (infection of gallbladder)
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Diarrhoea

40-49:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Injury
  3. Oedema peripheral (superficial swelling)
  4. Pain
  5. Pain in extremity
  6. Pulmonary embolism (blockage of the main artery of the lung)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9 people, 20.45%
  2. Thyroid Mass: 4 people, 9.09%
  3. Skin Exfoliation (removal of the oldest dead skin cells): 4 people, 9.09%
  4. Insomnia (sleeplessness): 4 people, 9.09%
  5. Indigestion: 4 people, 9.09%
  6. Acne (skin problems that cause pimples): 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Pentasa and Yasmin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pentasa and Yasmin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Yasmin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pentasa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Yasmin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and drospirenone; ethinyl estradiol (the active ingredients of Pentasa and Yasmin, respectively), and Pentasa and Yasmin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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