Pentoxifylline and Amaryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pentoxifylline (pentoxifylline) and Amaryl (glimepiride). Common drug interactions include oedema peripheral among females and arterial occlusive disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pentoxifylline and Amaryl. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

On Jul, 13, 2026

26 people who take Pentoxifylline and Amaryl together, and have interactions are studied.

Pentoxifylline and Amaryl drug interactions.

What are the common drug interactions of Pentoxifylline and Amaryl, by gender? *:

female:

Oedema peripheral (superficial swelling)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pleural effusion (water on the lungs)
Pleural fibrosis (formation of fibrous tissue in lung)
Postoperative fever
Pulmonary congestion (congestion in the lungs)
Renal failure acute (rapid kidney dysfunction)
Sensation of pressure
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)

male:

Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Cataract (clouding of the lens inside the eye)
Blood glucose increased
Blood pressure increased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sudden death
Chest pain
Drug hypersensitivity
Duodenal ulcer
Procedural complication

What are the common drug interactions of Pentoxifylline and Amaryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood cholesterol increased
Blood glucose increased
Sudden death
Alanine aminotransferase increased

50-59:

Chest pain
Drug hypersensitivity
Duodenal ulcer
Procedural complication
Oesophageal carcinoma (cancer tumour of oesophagus)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective
Drug intolerance (drug sensitivity)

60+:

Anxiety
Contusion (a type of hematoma of tissue in which capillaries)
Abdominal discomfort
Adverse drug reaction
Blood pressure decreased
Blood pressure increased
Cardiac failure congestive
Chronic kidney disease
Dyspepsia (indigestion)
Hyperhidrosis (abnormally increased sweating)

What are the existing conditions these people have? *

Gout (uric acid crystals building up in the body): 6 people, 23.08%
Chest Pain: 5 people, 19.23%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 19.23%
Hypoaesthesia (reduced sense of touch or sensation): 4 people, 15.38%
High Blood Pressure: 4 people, 15.38%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 15.38%
Dyslipidaemia (abnormal amount of lipids): 4 people, 15.38%
Type 2 Diabetes: 4 people, 15.38%
Hypersensitivity: 3 people, 11.54%
Hyperkalemia (damage to or disease of the kidney): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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