Pepcid ac and Mucinex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid ac (famotidine) and Mucinex (guaifenesin). Common drug interactions include obstruction among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid ac and Mucinex. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

On Jul, 15, 2026

76 people who take Pepcid ac and Mucinex together, and have interactions are studied.

Pepcid ac and Mucinex drug interactions.

What are the common drug interactions of Pepcid Ac and Mucinex, by gender? *:

female:

Obstruction
Oral herpes (viral infection of mouth)
Pain in jaw
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Photophobia (extreme sensitivity to light)
Renal failure (kidney dysfunction)
Rhinorrhoea (watery mucus discharge from the nose)
Seasonal allergy (allergic condition due to certain season)
Sinus congestion (blockage of sinus)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Infection
Renal injury (kidney injury)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Depression
Dizziness
Gout (uric acid crystals building up in the body)
Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Pepcid Ac and Mucinex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Panic attack
Peripheral swelling
Salivary gland enlargement (increased size of salivary gland)
Surgery
Swelling

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Infection
Influenza
Influenza like illness
Nephrogenic anaemia (anaemia due to kidney disease)
Oropharyngeal discomfort (pain or irritation of oropharynx)
Pain
Paranasal sinus hypersecretion
Pulmonary mass

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Vomiting
Weight increased
Infection
Bone pain
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Corneal erosion (failure of the cornea's outermost layer of epithelial cells to attach to the underlying)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 18 people, 23.68%
High Blood Pressure: 16 people, 21.05%
Pain: 14 people, 18.42%
Immunodeficiency Common Variable: 13 people, 17.11%
High Blood Cholesterol: 9 people, 11.84%
Depression: 9 people, 11.84%
Constipation: 7 people, 9.21%
Infection: 7 people, 9.21%
Indigestion: 7 people, 9.21%

* Approximation only. Some reports may have incomplete information.

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