Pepcid complete and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid complete (calcium carbonate; famotidine; magnesium hydroxide) and Premarin (estrogens, conjugated). Common drug interactions include chronic kidney disease among females.

The phase IV clinical study analyzes what interactions people have when they take Pepcid complete and Premarin. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid complete?

Pepcid complete has active ingredients of calcium carbonate; famotidine; magnesium hydroxide. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,884 Pepcid complete users. Check the latest studies of Pepcid complete.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 12, 2026

39 people who take Pepcid complete and Premarin together, and have interactions are studied.

Pepcid complete and Premarin drug interactions.

What are the common drug interactions of Pepcid Complete and Premarin, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Abscess (pus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Back pain
Bone disorder
Chest pain
Chronic gastritis (long lasting infection of stomach lining)
Disability
Dyspnoea (difficult or laboured respiration)

male:

n/a

What are the common drug interactions of Pepcid Complete and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blindness
Bone disorder
Bone fragmentation
Chest pain
Cutis laxa (connective tissue disorder in which the skin lacks elasticity and hangs in loose folds)
Deafness
Depression
Disability
Dizziness
Dry eye (lack of adequate tears)

50-59:

Anxiety
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac murmur (an heart sound in valve abnormality)
Cataract (clouding of the lens inside the eye)
Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypertension (high blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Oedema (fluid collection in tissue)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Abdominal pain
Abscess (pus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Bone disorder
Chest pain
Diarrhoea

What are the existing conditions these people have? *

Pain: 12 people, 30.77%
High Blood Cholesterol: 9 people, 23.08%
High Blood Pressure: 9 people, 23.08%
Multiple Allergies (allergy to multiple agents): 8 people, 20.51%
Headache (pain in head): 7 people, 17.95%
Stress And Anxiety: 6 people, 15.38%
Cough: 5 people, 12.82%
Depression: 5 people, 12.82%
Sleep Disorder: 5 people, 12.82%
Infection: 5 people, 12.82%

* Approximation only. Some reports may have incomplete information.

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