Pepcid and Drisdol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Drisdol (ergocalciferol). Common drug interactions include cellulitis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Drisdol. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.

On Jul, 26, 2026

70 people who take Pepcid and Drisdol together, and have interactions are studied.

What are the common drug interactions of Pepcid and Drisdol, by gender? *:

female:

Cellulitis (infection under the skin)
Chest discomfort
Dehydration (dryness resulting from the removal of water)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral swelling
Renal failure (kidney dysfunction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tinnitus (a ringing in the ears)
Dyspnoea (difficult or laboured respiration)
Essential hypertension (primary hypertension)

male:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Leukocytosis (increased white blood cells)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)
Asthenia (weakness)
Full blood count decreased

What are the common drug interactions of Pepcid and Drisdol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Nausea (feeling of having an urge to vomit)
Chest discomfort
Diarrhoea
Headache (pain in head)
Myalgia (muscle pain)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tinnitus (a ringing in the ears)
Pain

40-49:

Renal failure (kidney dysfunction)
Cellulitis (infection under the skin)
Renal injury (kidney injury)
Abdominal pain
Blindness
Blood alkaline phosphatase increased
Blood potassium decreased
Catheter site erythema (redness of skin at catheter site)
Catheter site pruritus (itching at the site)
Chest pain

50-59:

Emotional distress
Pain
Stress
Angioimmunoblastic t-cell lymphoma stage iv (mature t-cell cancer of the blood or lymph vessel-stage iv)
Calciphylaxis (is a syndrome with vascular calcium accumulation)
Drug hypersensitivity
Failure to thrive (inadequate weight gain and physical growth in children)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Localised oedema (fluid retention in a particular part of the body)

60+:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Renal tubular necrosis (death of kidney tubules)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Cellulitis (infection under the skin)
Death
Dehydration (dryness resulting from the removal of water)
Essential hypertension (primary hypertension)
Injection site pain
Muscle rupture (tear in muscle)
Peripheral swelling

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 20 people, 28.57%
Stress And Anxiety: 15 people, 21.43%
Pain: 13 people, 18.57%
Constipation: 12 people, 17.14%
High Blood Pressure: 11 people, 15.71%
Depression: 10 people, 14.29%
Muscle Spasms (muscle contraction): 10 people, 14.29%
Nausea And Vomiting: 9 people, 12.86%
Multiple Myeloma (cancer of the plasma cells): 8 people, 11.43%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 11.43%

* Approximation only. Some reports may have incomplete information.

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