Percocet and Spectazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Percocet (acetaminophen; oxycodone hydrochloride) and Spectazole (econazole nitrate). Common drug interactions include cellulitis among females and flank pain among males.

The phase IV clinical study analyzes what interactions people have when they take Percocet and Spectazole. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

What is Spectazole?

Spectazole has active ingredients of econazole nitrate. eHealthMe is studying from 248 Spectazole users. Check the latest studies of Spectazole.

On Jul, 12, 2026

38 people who take Percocet and Spectazole together, and have interactions are studied.

Percocet and Spectazole drug interactions.

What are the common drug interactions of Percocet and Spectazole, by gender? *:

female:

Cellulitis (infection under the skin)
Sensory loss (senses loss)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Escherichia infection (bacterial infection by escherichia coli)
Swelling
Appendicitis (inflammation of the appendix)
Aptyalism (deficiency or absence of saliva)
Asthma
Bone disorder
Bone erosion

male:

Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Pancreatitis (inflammation of pancreas)
Peptic ulcer
Weight decreased
Chronic kidney disease
Gait disturbance
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Pain in extremity
Renal failure (kidney dysfunction)

What are the common drug interactions of Percocet and Spectazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Gait disturbance
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Pain in extremity
Renal failure (kidney dysfunction)

50-59:

Foot deformity (functional disability of foot)
Hypoaesthesia (reduced sense of touch or sensation)
Sensory loss (senses loss)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Anxiety
Cellulitis (infection under the skin)
Escherichia infection (bacterial infection by escherichia coli)
Swelling
Appendicitis (inflammation of the appendix)
Aptyalism (deficiency or absence of saliva)

60+:

Blood pressure increased
Contusion (a type of hematoma of tissue in which capillaries)
Peptic ulcer
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Weight decreased
Epistaxis (bleed from the nose)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Laceration (tearing of soft body tissue)
Rectal haemorrhage (bleeding from anus)
Hodgkin's disease (cancer originating from white blood cells)

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 24 people, 63.16%
Osteoporosis (bones weak and more likely to break): 24 people, 63.16%
Thrombocytopenia (decrease of platelets in blood): 11 people, 28.95%
Rashes (redness): 5 people, 13.16%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 13.16%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.89%
Type 2 Diabetes: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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