Seroquel and Patanol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Patanol (olopatadine hydrochloride). Common drug interactions include deep vein thrombosis among females and hallucination among males.
The phase IV clinical study analyzes what interactions people have when they take Seroquel and Patanol. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
What is Patanol?
Patanol has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,339 Patanol users. Check the latest studies of Patanol.
67 people who take Seroquel and Patanol together, and have interactions are studied.

What are the common drug interactions of Seroquel and Patanol, by gender? *:
female:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dry mouth
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Epicondylitis (tennis elbow)
- Exostosis (formation of new bone on the surface of a bone)
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Hyperglycaemia (high blood sugar)
- Hypertriglyceridaemia (excess of triglycerides in the blood)
- Joint hyperextension (a joint is overstretched or ""bent backwards)
male:
- Hallucination (an experience involving the perception of something not present)
- Hypertension (high blood pressure)
- Pyrexia (fever)
- Renal cyst (kidney cyst)
- Renal impairment (severely reduced kidney function)
- Urinary tract infection
- Aggression
- Anxiety
- Chronic kidney disease
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
What are the common drug interactions of Seroquel and Patanol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Obesity (having too much body fat)
- Pancreatitis (inflammation of pancreas)
- Aggression
- Anxiety
- Impulsive behaviour
- Nasopharyngitis (inflammation of the nasopharynx)
- Negativism (negative thoughts)
20-29:
n/a
30-39:
- Agitation (state of anxiety or nervous excitement)
- Cough
- Pain
- Sneezing
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Anion gap increased
- Blood alkaline phosphatase increased
- Diabetic coma
40-49:
- Asthma
- Back pain
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Gastric disorder (disease of stomach)
- Hyperglycaemia (high blood sugar)
- Oedema peripheral (superficial swelling)
- Pancreatitis (inflammation of pancreas)
- Pulmonary congestion (congestion in the lungs)
- Pulmonary oedema (fluid accumulation in the lungs)
50-59:
- Dyspnoea exertional (breathlessness or shortness of breath)
- Erythema (redness of the skin)
- Eye disorder
- Fall
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gingival swelling (gums swelling)
- Hyperglycaemia (high blood sugar)
- Hypertension (high blood pressure)
- Influenza
- Influenza like illness
60+:
- Hallucination (an experience involving the perception of something not present)
- Fall
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dry mouth
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Epicondylitis (tennis elbow)
- Exostosis (formation of new bone on the surface of a bone)
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Femur fracture
What are the existing conditions these people have? *
- Pain: 17 people, 25.37%
- Depression: 15 people, 22.39%
- Stress And Anxiety: 14 people, 20.90%
- High Blood Pressure: 11 people, 16.42%
- Insomnia (sleeplessness): 9 people, 13.43%
- Immunodeficiency: 9 people, 13.43%
- Hypersensitivity: 8 people, 11.94%
- Back Pain: 7 people, 10.45%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 10.45%
- High Blood Cholesterol: 7 people, 10.45%
* Approximation only. Some reports may have incomplete information.
Do you take Seroquel and Patanol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Seroquel and Patanol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Patanol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Patanol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on quetiapine fumarate and olopatadine hydrochloride (the active ingredients of Seroquel and Patanol, respectively), and Seroquel and Patanol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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