Amlodipine and Abstral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Abstral (fentanyl citrate). Common drug interactions include cerebral haemorrhage among females and malignant neoplasm progression among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Abstral. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Abstral?

Abstral has active ingredients of fentanyl citrate. eHealthMe is studying from 1,390 Abstral users. Check the latest studies of Abstral.



On Jul, 12, 2026

35 people who take Amlodipine and Abstral together, and have interactions are studied.

Amlodipine and Abstral drug interactions.

What are the common drug interactions of Amlodipine and Abstral, by gender? *:

female:

  1. Cerebral haemorrhage (bleeding within the brain)
  2. Herpes zoster
  3. Plasma cell myeloma (cancer that begins in plasma cells)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Colon cancer stage iv
  7. Confusional state
  8. Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
  9. Bradycardia (abnormally slow heart action)
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  3. Diarrhoea
  4. Epistaxis (bleed from the nose)
  5. Gastric ulcer (stomach ulcer)
  6. General physical health deterioration (weak health status)
  7. Hepatic failure (liver failure)
  8. Hyperbilirubinaemia (excess of bilirubin in the blood)
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

What are the common drug interactions of Amlodipine and Abstral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Malignant neoplasm progression (cancer tumour came back)

50-59:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Death
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Constipation
  7. Epistaxis (bleed from the nose)
  8. Gastric ulcer (stomach ulcer)
  9. General physical health deterioration (weak health status)
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

60+:

  1. Cerebral haemorrhage (bleeding within the brain)
  2. Herpes zoster
  3. Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Bradycardia (abnormally slow heart action)
  6. Cholangitis (infection of the bile duct)
  7. Death
  8. Diarrhoea
  9. Dyspnoea (difficult or laboured respiration)
  10. Fall

What are the existing conditions these people have? *

  1. Cancer Pain: 7 people, 20.00%
  2. Hepatocellular Carcinoma (liver cancer): 6 people, 17.14%
  3. Constipation: 6 people, 17.14%
  4. Multiple Myeloma (cancer of the plasma cells): 5 people, 14.29%
  5. High Blood Cholesterol: 5 people, 14.29%
  6. Hepatitis B Surface Antigen Positive: 4 people, 11.43%
  7. Sleep Disorder: 4 people, 11.43%
  8. Hypokalemia (low potassium): 4 people, 11.43%
  9. Pain: 4 people, 11.43%
  10. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and Abstral?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amlodipine and Abstral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abstral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amlodipine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abstral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate and fentanyl citrate (the active ingredients of Amlodipine and Abstral, respectively), and Amlodipine and Abstral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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