Periactin and Neupogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Periactin (cyproheptadine hydrochloride) and Neupogen (filgrastim). Common drug interactions include deep vein thrombosis among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Periactin and Neupogen. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Periactin?

Periactin has active ingredients of cyproheptadine hydrochloride. It is often used in migraine. eHealthMe is studying from 2,214 Periactin users. Check the latest studies of Periactin.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

On Jul, 29, 2026

19 people who take Periactin and Neupogen together, and have interactions are studied.

Periactin and Neupogen drug interactions.

What are the common drug interactions of Periactin and Neupogen, by gender? *:

female:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemoglobin decreased
Leukopenia (less number of white blood cells in blood)

male:

Anaemia (lack of blood)
Pyrexia (fever)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Pharyngolaryngeal pain
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)

What are the common drug interactions of Periactin and Neupogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Night sweats (sweating in night)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Pancreatitis (inflammation of pancreas)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pericardial effusion (fluid around the heart)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Precocious puberty
Proteinuria (presence of protein in the urine)
Pyrexia (fever)

10-19:

Ileal stenosis (obstruction in the ileal)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Alcohol use
Cerebral haemorrhage (bleeding within the brain)
Concussion (short loss of normal brain function in response to a head injury)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Craniocerebral injury (injury to cranium and brain)
Fall
Joint lock
Laceration (tearing of soft body tissue)

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Pharyngolaryngeal pain
Pyrexia (fever)
Weight decreased
Anaemia (lack of blood)
Anti-erythropoietin antibody positive

50-59:

n/a

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Haemoglobin decreased
Leukopenia (less number of white blood cells in blood)

What are the existing conditions these people have? *

Hepatitis C: 8 people, 42.11%
Pre-Existing Disease: 3 people, 15.79%
Inflammatory Bowel Disease: 3 people, 15.79%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 15.79%
Leukopenia (less number of white blood cells in blood): 1 person, 5.26%
Gait Disturbance: 1 person, 5.26%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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