Peridex and Hctz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peridex (chlorhexidine gluconate) and Hctz (hydrochlorothiazide). Common drug interactions include amnesia among females and keratoacanthoma among males.

The phase IV clinical study analyzes what interactions people have when they take Peridex and Hctz. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

On Jul, 13, 2026

13 people who take Peridex and Hctz together, and have interactions are studied.

What are the common drug interactions of Peridex and Hctz, by gender? *:

female:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthropathy
Back pain
Blood cholesterol increased
Body height decreased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Concussion (short loss of normal brain function in response to a head injury)
Death
Diarrhoea
Diplopia (double vision)

male:

Keratoacanthoma (a common low-grade (unlikely to metastasize or invade) skin tumour that is believed to originate from the neck of the hair follicle)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Anal fistula
Head injury
White blood cell count decreased

What are the common drug interactions of Peridex and Hctz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Coagulopathy (blood's ability to clot is impaired)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Keratoacanthoma (a common low-grade (unlikely to metastasize or invade) skin tumour that is believed to originate from the neck of the hair follicle)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Death
Diarrhoea
Diplopia (double vision)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Epistaxis (bleed from the nose)
Eye disorder
Fall
Fungal infection

What are the existing conditions these people have? *

High Blood Cholesterol: 9 people, 69.23%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 7 people, 53.85%
Headache (pain in head): 7 people, 53.85%
Oedema (fluid collection in tissue): 7 people, 53.85%
Pain: 6 people, 46.15%
Blood Potassium Decreased: 6 people, 46.15%
Blepharitis (chronic inflammation of the eyelid): 5 people, 38.46%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 5 people, 38.46%
Itching: 5 people, 38.46%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 5 people, 38.46%

* Approximation only. Some reports may have incomplete information.

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