Permax and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Permax (pergolide mesylate) and Evista (raloxifene hydrochloride). Common drug interactions include alanine aminotransferase increased among females.

The phase IV clinical study analyzes what interactions people have when they take Permax and Evista. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Permax?

Permax has active ingredients of pergolide mesylate. eHealthMe is studying from 1,532 Permax users. Check the latest studies of Permax.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

11 people who take Permax and Evista together, and have interactions are studied.

What are the common drug interactions of Permax and Evista, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Fall
Difficulty in walking
Infection
Urinary retention (the inability to completely or partially empty the bladder)
Age indeterminate myocardial infarction (age indeterminate heart attack)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

n/a

What are the common drug interactions of Permax and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Fall
Difficulty in walking
Infection
Urinary retention (the inability to completely or partially empty the bladder)
Age indeterminate myocardial infarction (age indeterminate heart attack)
Blood creatinine increased

What are the existing conditions these people have? *

Parkinson's Disease: 10 people, 90.91%
Insomnia (sleeplessness): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Gallstones (stone formation by bile component): 1 person, 9.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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