Permax and Zonisamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Permax (pergolide mesylate) and Zonisamide (zonisamide). Common drug interactions include hallucination, visual among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Permax and Zonisamide. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Permax?

Permax has active ingredients of pergolide mesylate. eHealthMe is studying from 1,532 Permax users. Check the latest studies of Permax.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

On Jul, 11, 2026

18 people who take Permax and Zonisamide together, and have interactions are studied.

Permax and Zonisamide drug interactions.

What are the common drug interactions of Permax and Zonisamide, by gender? *:

female:

Hallucination, visual (seeing things that aren't there)
Delusion (a false belief or opinion)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Abasia (inability to walk)
Decreased appetite
Delusional disorder, persecutory type (a belief that they (or someone close to them) are being mistreated)
Erythromelalgia (episodes of pain, redness, and swelling in various parts of the body)
Obsessive thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry)

male:

Fall
Impulsive behaviour
Bereavement reaction
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Dyskinesia (abnormality or impairment of voluntary movement)

What are the common drug interactions of Permax and Zonisamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Decreased appetite

30-39:

n/a

40-49:

Decreased appetite

50-59:

Affect lability (emotional incontinence)
Antisocial personality disorder
Bereavement reaction
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Chest pain
Delusional disorder, persecutory type (a belief that they (or someone close to them) are being mistreated)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Dyskinesia (abnormality or impairment of voluntary movement)

60+:

Completed suicide (act of taking one's own life)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Rash
Rash erythematous (redness of the skin)
Skin reaction
Sputum discoloured
Subdural haematoma (blood collects between the skull and the surface of the brain)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Viral infection
Tendon rupture (tear of tendon)

What are the existing conditions these people have? *

Parkinson's Disease: 17 people, 94.44%
Bacterial Infection: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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