Phenergan and Aggrenox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phenergan (promethazine hydrochloride) and Aggrenox (aspirin; dipyridamole). Common drug interactions include abdominal pain among females and gastric ulcer among males.

The phase IV clinical study analyzes what interactions people have when they take Phenergan and Aggrenox. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

What is Aggrenox?

Aggrenox has active ingredients of aspirin; dipyridamole. It is often used in stroke. eHealthMe is studying from 7,654 Aggrenox users. Check the latest studies of Aggrenox.

On Jul, 15, 2026

22 people who take Phenergan and Aggrenox together, and have interactions are studied.

Phenergan and Aggrenox drug interactions.

What are the common drug interactions of Phenergan and Aggrenox, by gender? *:

female:

Abdominal pain
Anaemia (lack of blood)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Balance disorder
Cardiogenic shock (inadequate circulation of blood)
Cholecystitis acute (rapid infection of gallbladder)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Congestive cardiomyopathy (weakening of heart muscle)

male:

Gastric ulcer (stomach ulcer)
Haematemesis (vomiting of blood)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Pleural effusion (water on the lungs)
Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Phenergan and Aggrenox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Bladder dilatation
Catheter site infection (infection at the site of insertion)
Culture urine positive
Diarrhoea
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Gastric ulcer (stomach ulcer)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Congestive cardiomyopathy (weakening of heart muscle)
Dyspnoea (difficult or laboured respiration)
Enterovesical fistula
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hyperkalaemia (damage to or disease of the kidney)
Hypotension (abnormally low blood pressure)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 18.18%
Pain: 3 people, 13.64%
Nausea And Vomiting: 3 people, 13.64%
High Blood Pressure: 3 people, 13.64%
Heart Attack: 3 people, 13.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
Constipation: 3 people, 13.64%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 9.09%
Osteoporosis (bones weak and more likely to break): 2 people, 9.09%
Migraine (headache): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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