Phenylephrine hydrochloride and Tobramycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phenylephrine hydrochloride (phenylephrine hydrochloride) and Tobramycin (tobramycin). Common drug interactions include maternal exposure during pregnancy among females and conjunctivitis among males.

The phase IV clinical study analyzes what interactions people have when they take Phenylephrine hydrochloride and Tobramycin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Phenylephrine hydrochloride?

Phenylephrine hydrochloride has active ingredients of phenylephrine hydrochloride. eHealthMe is studying from 1,240 Phenylephrine hydrochloride users. Check the latest studies of Phenylephrine hydrochloride.

What is Tobramycin?

Tobramycin has active ingredients of tobramycin. It is often used in cystic fibrosis. eHealthMe is studying from 3,579 Tobramycin users. Check the latest studies of Tobramycin.

On Jul, 09, 2026

14 people who take Phenylephrine hydrochloride and Tobramycin together, and have interactions are studied.

Phenylephrine hydrochloride and Tobramycin drug interactions.

What are the common drug interactions of Phenylephrine Hydrochloride and Tobramycin, by gender? *:

female:

Maternal exposure during pregnancy (use of substance during pregnancy)
Abortion spontaneous (naturally occurring miscarriage)
Anaphylactic reaction (serious allergic reaction)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Drug ineffective
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hyperreflexia (overactive or over responsive reflexes)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Muscle contractions involuntary (uncontrolled muscle contraction)

male:

Conjunctivitis (pink eye)
Erythema (redness of the skin)
Eye discharge
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pain
Pyrexia (fever)
Throat irritation
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Rash erythematous (redness of the skin)

What are the common drug interactions of Phenylephrine Hydrochloride and Tobramycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Throat irritation
Abortion spontaneous (naturally occurring miscarriage)
Anaphylactic reaction (serious allergic reaction)
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
Drug ineffective
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hyperreflexia (overactive or over responsive reflexes)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Muscle contractions involuntary (uncontrolled muscle contraction)

40-49:

n/a

50-59:

n/a

60+:

Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Rash erythematous (redness of the skin)

What are the existing conditions these people have? *

Uterine Contractions During Pregnancy: 10 people, 71.43%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 1 person, 7.14%
Nausea And Vomiting: 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Morning Sickness (sickness in morning during pregnancy): 1 person, 7.14%
Migraine (headache): 1 person, 7.14%
Hyperemesis Gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance): 1 person, 7.14%
Body Temperature Increased: 1 person, 7.14%
Age-Related Macular Degeneration: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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