Vfend and Hepatic encephalopathy - a phase IV clinical study of FDA data

Summary:

Hepatic encephalopathy is reported as a side effect among people who take Vfend (voriconazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Fungizone, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Hepatic encephalopathy when taking Vfend. It is created by eHealthMe based on reports of 12,081 people who have side effects when taking Vfend from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Hepatic encephalopathy?

Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure) is found to be associated with 916 drugs and 1,259 conditions by eHealthMe. Check the latest studies of Hepatic encephalopathy.

On Jul, 09, 2026

12,081 people reported to have side effects when taking Vfend.
Among them, 23 people (0.19%) have Hepatic encephalopathy.

Could Vfend cause Hepatic encephalopathy?

Among these 23 people:

How long have people been on Vfend when they have Hepatic encephalopathy? *

What is the gender of people who have Hepatic encephalopathy when taking Vfend? *

female: 28.57 %
male: 71.43 %

What is the age of people who have Hepatic encephalopathy when taking Vfend? *

What are other drugs people take besides Vfend? *

What are other side effects people have besides Hepatic encephalopathy? *

Hepatic Failure (liver failure): 9 people, 39.13%
Hepatic Steatosis (fatty liver disease): 6 people, 26.09%
Acute Kidney Failure: 6 people, 26.09%
Multi-Organ Failure (multisystem organ failure): 6 people, 26.09%
Cardiac Disorder: 5 people, 21.74%
Blood Bilirubin Increased: 5 people, 21.74%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 5 people, 21.74%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 21.74%
Thrombocytopenia (decrease of platelets in blood): 5 people, 21.74%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 17.39%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 10 people, 43.48%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 7 people, 30.43%
Acute Leukaemia (blood cancer): 4 people, 17.39%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 17.39%
Pulmonary Aspergilloma (Mycetoma) (mass caused by a fungal infection that usually grows in lung): 3 people, 13.04%
Intraocular Pressure Decreased: 3 people, 13.04%
Infection: 3 people, 13.04%
Fungal Infection: 3 people, 13.04%
Agitation (state of anxiety or nervous excitement): 1 person, 4.35%
Antithrombin Iii Decreased: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Vfend and have Hepatic encephalopathy?

- Check whether Hepatic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vfend:

Vfend (12,128 reports)

Browse all side effects of Vfend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic encephalopathy:

Hepatic encephalopathy (916 drugs)

Browse all the conditions that are associated with Hepatic encephalopathy:

Hepatic encephalopathy (1,259 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on voriconazole (the active ingredients of Vfend) and Vfend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.