Phoslo and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Phoslo (calcium acetate) and Clonazepam (clonazepam). Common drug interactions include skin tightness among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Phoslo and Clonazepam. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.
What is Phoslo?
Phoslo has active ingredients of calcium acetate. eHealthMe is studying from 4,291 Phoslo users. Check the latest studies of Phoslo.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,271 Clonazepam users. Check the latest studies of Clonazepam.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
81 people who take Phoslo and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Phoslo and Clonazepam, by gender? *:
female:
- Skin tightness
- Abdominal pain
- Dyspnoea (difficult or laboured respiration)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Emotional distress
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Activities of daily living impaired
- Arrhythmia (irregular heartbeat)
male:
- Dyspnoea (difficult or laboured respiration)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Diarrhoea
- Dizziness
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Loss of consciousness
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pallor
What are the common drug interactions of Phoslo and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Depression
- Hyperaesthesia
- Hyperglycaemia (high blood sugar)
- Neuropathy peripheral (surface nerve damage)
- Pain
30-39:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Back pain
- Blood pressure fluctuation
- Diarrhoea
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Joint contracture (a permanent shortening of a muscle or joint)
40-49:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Depression
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pneumonia
- Anaemia (lack of blood)
- Anaphylactic reaction (serious allergic reaction)
- Asthma
- Blood glucose decreased
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Chest pain
- Dry skin
- Emotional distress
- Hypoaesthesia (reduced sense of touch or sensation)
- Joint contracture (a permanent shortening of a muscle or joint)
- Joint stiffness
- Muscular weakness (muscle weakness)
- Oedema peripheral (superficial swelling)
- Pain of skin
60+:
- Dyspnoea (difficult or laboured respiration)
- Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
- Renal failure chronic (long lasting kidney dysfunction)
- Serum ferritin increased
- Abdominal pain
- Decreased appetite
- Fluid overload (too much fluid in the blood)
- Nausea (feeling of having an urge to vomit)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Pain
What are the existing conditions these people have? *
- Pain: 10 people, 12.35%
- Nuclear Magnetic Resonance Imaging Brain: 8 people, 9.88%
- Diabetes: 7 people, 8.64%
- Anaemia (lack of blood): 7 people, 8.64%
- Hyperkalemia (damage to or disease of the kidney): 6 people, 7.41%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Phoslo and Clonazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Phoslo (4,291 reports)
- Clonazepam (146,271 reports)
Browse all drug interactions of Phoslo and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Phoslo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Phoslo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on calcium acetate and clonazepam (the active ingredients of Phoslo and Clonazepam, respectively), and Phoslo and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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