Phoslo and Glucotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phoslo (calcium acetate) and Glucotrol (glipizide). Common drug interactions include pruritus among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Phoslo and Glucotrol. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Phoslo?

Phoslo has active ingredients of calcium acetate. eHealthMe is studying from 4,291 Phoslo users. Check the latest studies of Phoslo.

What is Glucotrol?

Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.

On Aug, 11, 2026

52 people who take Phoslo and Glucotrol together, and have interactions are studied.

What are the common drug interactions of Phoslo and Glucotrol, by gender? *:

female:

Pruritus (severe itching of the skin)
Renal disorder (kidney disease)
Renal failure acute (rapid kidney dysfunction)
Renal injury (kidney injury)
Stress
Vomiting
Abdominal pain upper
Activities of daily living impaired
Apnoea (suspension of external breathing)
Blood creatinine increased

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Joint contracture (a permanent shortening of a muscle or joint)
Skin fibrosis (fibrous tissue formation on skin)
Skin tightness
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Aspartate aminotransferase increased
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Blood alkaline phosphatase nos increased

What are the common drug interactions of Phoslo and Glucotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Oedema peripheral (superficial swelling)
Skin hypertrophy (skin cells enlarges)
Skin induration (an abnormally hard spot or area on the skin)
Pain of skin
Skin atrophy (wasting of skin)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin ulcer

50-59:

Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Emotional distress
Hyperkeratosis (thickening of the outer layer of the skin)
Joint range of motion decreased (disease of joint movement)
Mobility decreased (ability to move is reduced)
Parakeratosis
Pitting oedema (skin discoloration)

60+:

Asthenia (weakness)
Death
Constipation
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fear
Fluid overload (too much fluid in the blood)
Heart injury
Hepatic failure (liver failure)
Hepatocellular damage (liver damage)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 13.46%
High Blood Cholesterol: 7 people, 13.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 13.46%
Type 2 Diabetes: 6 people, 11.54%
Pain: 6 people, 11.54%
Multiple Allergies (allergy to multiple agents): 5 people, 9.62%
Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 9.62%
Hot Flush (sudden feelings of heat): 4 people, 7.69%
Dyspnea (difficult or laboured breathing): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Phoslo and Glucotrol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously