Phoslo and Promethazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phoslo (calcium acetate) and Promethazine (promethazine hydrochloride). Common drug interactions include neuropathy peripheral among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Phoslo and Promethazine. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Phoslo?

Phoslo has active ingredients of calcium acetate. eHealthMe is studying from 4,291 Phoslo users. Check the latest studies of Phoslo.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

On Aug, 02, 2026

38 people who take Phoslo and Promethazine together, and have interactions are studied.

Phoslo and Promethazine drug interactions.

What are the common drug interactions of Phoslo and Promethazine, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Oxygen saturation decreased
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Peripheral vascular disorder
Postoperative wound infection
Pulmonary oedema (fluid accumulation in the lungs)
Purulent discharge (discharge that contains pus)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Asthenia (weakness)
Deformity (disfigurement)
Depression
Drug ineffective
General physical health deterioration (weak health status)
Haematocrit

What are the common drug interactions of Phoslo and Promethazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Sepsis (a severe blood infection that can lead to organ failure and death)

30-39:

Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Glomerulonephritis membranoproliferative (a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (gbm) thickening)
Hospitalisation
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Drug ineffective
Haematocrit
Haemoglobin decreased
Nephrogenic anaemia (anaemia due to kidney disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Depression

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal injury (kidney injury)
Anxiety
Pain
Nephropathy (damage to or disease of a kidney)
Abdominal discomfort
Constipation

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Carotid artery stenosis (narrowing of carotid artery)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Dementia (madness)
Drug effect decreased
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 47.37%
High Blood Pressure: 15 people, 39.47%
Pain: 11 people, 28.95%
Hiv Infection: 6 people, 15.79%
Infection: 5 people, 13.16%
Diabetes: 4 people, 10.53%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 7.89%
Multiple Allergies (allergy to multiple agents): 3 people, 7.89%
Asthma: 3 people, 7.89%
Bacterial Infection: 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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