Plendil and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Plendil (felodipine), especially for people who are female, 60+ old, also take Calcium, and have Osteoporosis.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Plendil. It is created by eHealthMe based on reports of 4,897 people who have side effects when taking Plendil from the FDA, and is updated regularly.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,181 drugs and 1,743 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

On Aug, 02, 2026

4,897 people reported to have side effects when taking Plendil.
Among them, 17 people (0.35%) have Peripheral swelling.

Could Plendil cause Peripheral swelling?

Among these 17 people:

What is the gender of people who have Peripheral swelling when taking Plendil? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Peripheral swelling when taking Plendil? *

What are other drugs people take besides Plendil? *

What are other side effects people have besides Peripheral swelling? *

Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 7 people, 41.18%
Swelling: 7 people, 41.18%
Dyspnea (difficult or laboured breathing): 3 people, 17.65%
Rashes (redness): 3 people, 17.65%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 11.76%
Dyspnea Exertional: 2 people, 11.76%
Pain In Extremity: 2 people, 11.76%
Electrocardiogram Abnormal: 1 person, 5.88%
Electrocardiogram St Segment Depression: 1 person, 5.88%
Electrocardiogram T Wave Abnormal: 1 person, 5.88%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 6 people, 35.29%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.76%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 1 person, 5.88%
Stable Angina (a constant chest pain): 1 person, 5.88%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Prostate Cancer: 1 person, 5.88%
Pain: 1 person, 5.88%
Osteoporotic Fracture (fracture due to weak bone): 1 person, 5.88%
Oedema (fluid collection in tissue): 1 person, 5.88%
High Blood Cholesterol: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Plendil and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plendil:

Plendil (4,990 reports)

Browse all side effects of Plendil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,181 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,743 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on felodipine (the active ingredients of Plendil) and Plendil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.