Baclofen and Enulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Enulose (lactulose). Common drug interactions include nausea among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Enulose. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.



On Aug, 02, 2026

38 people who take Baclofen and Enulose together, and have interactions are studied.

Baclofen and Enulose drug interactions.

What are the common drug interactions of Baclofen and Enulose, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Osteoporosis (bones weak and more likely to break)
  3. Tardive dyskinesia (a disorder that involves involuntary movements)
  4. Vomiting
  5. Weight decreased
  6. Abdominal pain
  7. Abdominal pain upper
  8. Adverse drug reaction
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Anaemia (lack of blood)

male:

  1. Pneumonia
  2. Ileus (a painful obstruction of the ileum or other part of the intestine)
  3. Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
  4. Coagulopathy (blood's ability to clot is impaired)
  5. Confusional state
  6. Cytomegalovirus infection
  7. Dizziness
  8. Epistaxis (bleed from the nose)
  9. Fluid overload (too much fluid in the blood)
  10. Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)

What are the common drug interactions of Baclofen and Enulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Arthralgia (joint pain)
  3. Back pain
  4. Blood triglycerides increased
  5. Bone pain
  6. Cardiac murmur (an heart sound in valve abnormality)
  7. Chest discomfort
  8. Decreased activity
  9. Decreased appetite
  10. Depression

40-49:

  1. Septic shock (shock due to blood infection)
  2. Memory impairment
  3. Anaemia (lack of blood)
  4. Dizziness
  5. Hypotension (abnormally low blood pressure)
  6. Nausea (feeling of having an urge to vomit)
  7. Abdominal pain
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Aspartate aminotransferase increased
  10. Blood bilirubin increased

50-59:

  1. Cytomegalovirus infection
  2. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  3. Pneumocystis carinii pneumonia (pneumonia occurring in infants or in persons with impaired immune systems)
  4. Colon cancer metastatic (cancer of colon spreads to other part of body)
  5. Intestinal obstruction
  6. Pneumonia
  7. Renal failure (kidney dysfunction)
  8. Alanine aminotransferase increased
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Anaemia (lack of blood)

60+:

  1. Abdominal pain
  2. Chronic kidney disease
  3. Angina pectoris (chest pain due to ischemia of the heart muscle)
  4. Anxiety
  5. Asthenia (weakness)
  6. Blood pressure increased
  7. Brain injury
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Chest pain
  10. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the existing conditions these people have? *

  1. Pain: 10 people, 26.32%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 26.32%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 26.32%
  4. Stress And Anxiety: 7 people, 18.42%
  5. Headache (pain in head): 6 people, 15.79%
  6. High Blood Pressure: 6 people, 15.79%
  7. Depression: 6 people, 15.79%
  8. Sleep Apnea Syndrome: 5 people, 13.16%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 5 people, 13.16%
  10. Nausea (feeling of having an urge to vomit): 4 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and Enulose?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Baclofen and Enulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Enulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Enulose and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on baclofen and lactulose (the active ingredients of Baclofen and Enulose, respectively), and Baclofen and Enulose (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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