Senna and Tobi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Tobi (tobramycin). Common drug interactions include affective disorder among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Tobi. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Tobi?

Tobi has active ingredients of tobramycin. eHealthMe is studying from 10,011 Tobi users. Check the latest studies of Tobi.

On Aug, 02, 2026

36 people who take Senna and Tobi together, and have interactions are studied.

What are the common drug interactions of Senna and Tobi, by gender? *:

female:

Affective disorder (mental disorder)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alveolar osteitis (complication of wound healing following extraction of a tooth)
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Blood magnesium decreased
Blood sodium decreased

male:

Cough
Dyspnoea (difficult or laboured respiration)
Asthma
Blood pressure decreased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Chest discomfort
Chills (felling of cold)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Clubbing (deformity of the fingers and fingernails)
Cystic fibrosis related diabetes

What are the common drug interactions of Senna and Tobi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Suicidal ideation
Abdominal pain upper
Anxiety
Depression
Hypnopompic hallucination
Hypoaesthesia (reduced sense of touch or sensation)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Panic attack
Sleep paralysis (waking up and unable to move or speak)

20-29:

Abdominal pain
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Blood glucose increased
Bronchial wall thickening
Epistaxis (bleed from the nose)
Pancreatitis acute (sudden inflammation of pancreas)
Pulmonary mass
Hemiparesis (weakness on one side of the body)
Pain
Syringomyelia (cavity forms within the spinal cord)

30-39:

Dyspnoea (difficult or laboured respiration)
Productive cough
Cystic fibrosis (disease of the secretary glands)
Abdominal pain
Asthenia (weakness)
Chest pain
Confusional state
Cough
Decreased appetite
Dizziness

40-49:

Dyspnoea (difficult or laboured respiration)
Social problem

50-59:

Arthropathy
Exostosis (formation of new bone on the surface of a bone)
Pain in extremity
Shoulder operation
Arthritis (form of joint disorder that involves inflammation of one or more joints)

60+:

Depression
Asthenia (weakness)
Alveolar osteitis (complication of wound healing following extraction of a tooth)
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Blood magnesium decreased

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 30 people, 83.33%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 7 people, 19.44%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 7 people, 19.44%
Sinusitis (inflammation of sinus): 6 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.67%
Stress And Anxiety: 2 people, 5.56%
Seasonal Allergy (allergic condition due to certain season): 2 people, 5.56%
Panic Disorder: 2 people, 5.56%
Pain: 2 people, 5.56%
Insomnia (sleeplessness): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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