Efavirenz and Cognitive disorder - a phase IV clinical study of FDA data

Summary:

Cognitive disorder is reported as a side effect among people who take Efavirenz (efavirenz), especially for people who are male, 50-59 old, have been taking the drug for 6 - 12 months also take Lamivudine, and have Neurosyphilis.

The phase IV clinical study analyzes which people have Cognitive disorder when taking Efavirenz. It is created by eHealthMe based on reports of 15,449 people who have side effects when taking Efavirenz from the FDA, and is updated regularly.

What is Efavirenz?

Efavirenz has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 15,501 Efavirenz users. Check the latest studies of Efavirenz.

What is Cognitive disorder?

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving) is found to be associated with 1,649 drugs and 1,727 conditions by eHealthMe. Check the latest studies of Cognitive disorder.

On Aug, 02, 2026

15,449 people reported to have side effects when taking Efavirenz.
Among them, 32 people (0.21%) have Cognitive disorder.

Could Efavirenz cause Cognitive disorder?

Among these 32 people:

How long have people been on Efavirenz when they have Cognitive disorder? *

What is the gender of people who have Cognitive disorder when taking Efavirenz? *

female: 7.41 %
male: 92.59 %

What is the age of people who have Cognitive disorder when taking Efavirenz? *

What are other drugs people take besides Efavirenz? *

Lamivudine: 16 people, 50.00%
Abacavir: 12 people, 37.50%
Zidovudine: 10 people, 31.25%
Ritonavir: 6 people, 18.75%
Combivir: 5 people, 15.62%
Abacavir Sulfate: 2 people, 6.25%
Prozac: 2 people, 6.25%
Zantac: 2 people, 6.25%
Lamivudine And Zidovudine: 2 people, 6.25%
Amlodipine: 2 people, 6.25%

What are other side effects people have besides Cognitive disorder? *

Confusional State: 12 people, 37.50%
Mobility Decreased (ability to move is reduced): 11 people, 34.38%
Aids Encephalopathy (malfunction of the brain as a result of hiv infection, variety of cognitive, motor, and behavioural abnormalities): 10 people, 31.25%
Blood Hiv Rna Increased: 9 people, 28.12%
Speech Impairment (Adult) (inability to speak (adult)): 9 people, 28.12%
Multiple-Drug Resistance: 8 people, 25.00%
Disturbance In Attention: 8 people, 25.00%
Fatigue (feeling of tiredness): 8 people, 25.00%
Depression: 7 people, 21.88%
Intentional Self-Injury: 6 people, 18.75%

What are the existing conditions these people have? *

Neurosyphilis (an infection of the brain or spinal cord caused by the bacterium treponema pallidum): 2 people, 6.25%
Meningitis Cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 1 person, 3.12%
High Blood Pressure: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Efavirenz and have Cognitive disorder?

- Check whether Cognitive disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Efavirenz:

Efavirenz (15,501 reports)

Browse all side effects of Efavirenz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cognitive disorder:

Cognitive disorder (1,649 drugs)

Browse all the conditions that are associated with Cognitive disorder:

Cognitive disorder (1,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on efavirenz (the active ingredients of Efavirenz) and Efavirenz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.