Pimecrolimus and Lorazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pimecrolimus (pimecrolimus) and Lorazepam (lorazepam). Common drug interactions include asthenia among females and body temperature decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Pimecrolimus and Lorazepam. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Pimecrolimus?

Pimecrolimus has active ingredients of pimecrolimus. eHealthMe is studying from 1,358 Pimecrolimus users. Check the latest studies of Pimecrolimus.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 14, 2026

34 people who take Pimecrolimus and Lorazepam together, and have interactions are studied.

Pimecrolimus and Lorazepam drug interactions.

What are the common drug interactions of Pimecrolimus and Lorazepam, by gender? *:

female:

  1. Asthenia (weakness)
  2. Bradycardia (abnormally slow heart action)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Chills (felling of cold)
  5. Completed suicide (act of taking one's own life)
  6. Dizziness
  7. Ear infection
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  9. Eye disorder
  10. Eye pain

male:

  1. Body temperature decreased
  2. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  3. Skin exfoliation (removal of the oldest dead skin cells)
  4. Skin lesion
  5. Skin plaque (red, scaly patches to appear on the skin)
  6. Transient acantholytic dermatosis (a skin condition that causes the appearance of small, red spots on chest and back)
  7. Urticaria (rash of round, red welts on the skin that itch intensely)
  8. Injection site reaction
  9. Aortic arteriosclerosis (hardening of the aortic arteries)
  10. Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)

What are the common drug interactions of Pimecrolimus and Lorazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Dry eye (lack of adequate tears)
  2. Eye allergy

20-29:

n/a

30-39:

  1. Poor quality sleep
  2. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  3. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  4. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
  7. Vitamin d deficiency
  8. Weight increased
  9. Bradycardia (abnormally slow heart action)
  10. Completed suicide (act of taking one's own life)

40-49:

  1. Candida sepsis (candida in blood stream)
  2. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  5. Bacteraemia (presence of bacteria in the blood)
  6. Blood bilirubin increased
  7. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  8. Fluid overload (too much fluid in the blood)
  9. Lactic acidosis (low ph in body tissues)
  10. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)

50-59:

  1. Body temperature decreased
  2. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  3. Discomfort
  4. Drug ineffective
  5. Erythema (redness of the skin)
  6. Haemorrhage (bleeding)
  7. Intertrigo (inflammation (rash) of the body folds (adjacent areas of skin))
  8. Papule
  9. Pruritus (severe itching of the skin)
  10. Skin discolouration (change of skin colour)

60+:

  1. Headache (pain in head)
  2. Arthralgia (joint pain)
  3. Lymphadenopathy (disease or enlargement of lymph nodes)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Muscle spasms (muscle contraction)
  6. Nausea (feeling of having an urge to vomit)
  7. Pruritus (severe itching of the skin)
  8. Rash
  9. Respiratory disorder (respiratory disease)
  10. Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

  1. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 9 people, 26.47%
  2. Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 14.71%
  3. Joint Injury: 5 people, 14.71%
  4. Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 3 people, 8.82%
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 8.82%
  6. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 8.82%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 8.82%
  8. Asthma: 3 people, 8.82%
  9. Adenovirus Infection: 3 people, 8.82%
  10. Respiratory Disorder (respiratory disease): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Pimecrolimus and Lorazepam?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pimecrolimus and Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pimecrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pimecrolimus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pimecrolimus and lorazepam (the active ingredients of Pimecrolimus and Lorazepam, respectively), and Pimecrolimus and Lorazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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