Pioglitazone and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pioglitazone (pioglitazone hydrochloride) and Adalat (nifedipine). Common drug interactions include palpitations among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Pioglitazone and Adalat. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

On Jul, 28, 2026

31 people who take Pioglitazone and Adalat together, and have interactions are studied.

Pioglitazone and Adalat drug interactions.

What are the common drug interactions of Pioglitazone and Adalat, by gender? *:

female:

Palpitations (feelings or sensations that your heart is pounding or racing)
Cholangitis (infection of the bile duct)
Septic shock (shock due to blood infection)
Abdominal pain upper
Anaemia (lack of blood)
International normalised ratio increased
Melaena (the passage of black, tarry stools)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Syncope (loss of consciousness with an inability to maintain postural tone)
Angina pectoris (chest pain due to ischemia of the heart muscle)

male:

Pyrexia (fever)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hepatic lesion
Hyperkalaemia (damage to or disease of the kidney)
Inappropriate antidiuretic hormone secretion
Neoplasm malignant (cancer tumour)
Respiratory depression (respiration has a rate below 12 breaths)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Splenomegaly (enlargement of spleen)
Bladder cancer

What are the common drug interactions of Pioglitazone and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Drug ineffective
Vascular pseudoaneurysm ruptured (leakage of arterial blood from an artery into the surrounding tissue with a continuing communication between the originating artery and the resultant adjacent cavity)

60+:

Pyrexia (fever)
Palpitations (feelings or sensations that your heart is pounding or racing)
Anaemia (lack of blood)
International normalised ratio increased
Melaena (the passage of black, tarry stools)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Syncope (loss of consciousness with an inability to maintain postural tone)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Bladder neoplasm (bladder tumour)
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 6 people, 19.35%
White Blood Cell Count Decreased: 5 people, 16.13%
Type 2 Diabetes: 5 people, 16.13%
Thrombocytopenia (decrease of platelets in blood): 5 people, 16.13%
Neuropathy Peripheral (surface nerve damage): 5 people, 16.13%
Nausea And Vomiting: 5 people, 16.13%
Leukopenia (less number of white blood cells in blood): 5 people, 16.13%
Infection: 5 people, 16.13%
Hypersensitivity: 5 people, 16.13%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 5 people, 16.13%

* Approximation only. Some reports may have incomplete information.

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