Piperacillin and tazobactam and Sprycel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Piperacillin and tazobactam (piperacillin sodium; tazobactam sodium) and Sprycel (dasatinib). Common drug interactions include pyrexia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Piperacillin and tazobactam and Sprycel. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Piperacillin and tazobactam?

Piperacillin and tazobactam has active ingredients of piperacillin sodium; tazobactam sodium. eHealthMe is studying from 12,660 Piperacillin and tazobactam users. Check the latest studies of Piperacillin and tazobactam.

What is Sprycel?

Sprycel has active ingredients of dasatinib. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 29,788 Sprycel users. Check the latest studies of Sprycel.



On Jul, 13, 2026

13 people who take Piperacillin and tazobactam and Sprycel together, and have interactions are studied.

Piperacillin and tazobactam and Sprycel drug interactions.

What are the common drug interactions of Piperacillin And Tazobactam and Sprycel, by gender? *:

female:

  1. Pyrexia (fever)
  2. Pleural effusion (water on the lungs)
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  4. Anal ulcer
  5. Bacteraemia (presence of bacteria in the blood)
  6. Blast cell crisis
  7. Cardiac failure acute
  8. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  9. Febrile neutropenia (fever with reduced white blood cells)
  10. Fungal infection

male:

  1. Anaemia (lack of blood)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Oral herpes (viral infection of mouth)
  4. Pericardial effusion (fluid around the heart)
  5. Platelet count decreased
  6. Pleural effusion (water on the lungs)
  7. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  8. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
  9. Pneumonia viral
  10. Pulmonary haemorrhage (acute bleeding from the lung)

What are the common drug interactions of Piperacillin And Tazobactam and Sprycel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anal ulcer
  2. Blast cell crisis
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Oral herpes (viral infection of mouth)
  6. Pain
  7. Pyrexia (fever)

20-29:

  1. Anaemia (lack of blood)
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  4. Eyelid oedema (eyelids are swollen and contain excessive fluid)
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Generalised oedema (swelling all over the body)
  7. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  8. Headache (pain in head)
  9. Interstitial lung disease
  10. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

30-39:

n/a

40-49:

n/a

50-59:

  1. Pyrexia (fever)
  2. Renal disorder (kidney disease)
  3. Vomiting
  4. Serum ferritin increased
  5. Cryptococcosis (potentially fatal fungal disease)
  6. Dementia (madness)
  7. Folliculitis (infection of hair root)
  8. Herpes zoster
  9. Hypocoagulable state (abnormality of blood coagulation that increases the risk of thrombosis)
  10. Hypokalaemia (low potassium)

60+:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Cardiac failure acute
  4. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  5. Fungal infection
  6. Pleural effusion (water on the lungs)
  7. Toxic skin eruption (skin breakdown due to toxic substance)
  8. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  9. Rash pustular (redness with pustules)

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 30.77%
  2. Systemic Mycosis (fungal infections of the body): 3 people, 23.08%
  3. Leukaemia (blood or bone marrow cancer): 3 people, 23.08%
  4. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 23.08%
  5. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 23.08%
  6. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 7.69%
  7. Acute Leukaemia (blood cancer): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Piperacillin and tazobactam and Sprycel:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Piperacillin and tazobactam:

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Browse all side effects of Sprycel:

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Browse all interactions between Piperacillin and tazobactam and drugs from A to Z:

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Browse all interactions between Sprycel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on piperacillin sodium; tazobactam sodium and dasatinib (the active ingredients of Piperacillin and tazobactam and Sprycel, respectively), and Piperacillin and tazobactam and Sprycel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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