Renvela and Fenofibrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renvela (sevelamer carbonate) and Fenofibrate (fenofibrate). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Renvela and Fenofibrate. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Renvela?

Renvela has active ingredients of sevelamer carbonate. eHealthMe is studying from 10,923 Renvela users. Check the latest studies of Renvela.

What is Fenofibrate?

Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,456 Fenofibrate users. Check the latest studies of Fenofibrate.

On Jul, 13, 2026

61 people who take Renvela and Fenofibrate together, and have interactions are studied.

Renvela and Fenofibrate drug interactions.

What are the common drug interactions of Renvela and Fenofibrate, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Blood calcium decreased
Renal injury (kidney injury)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Pain
Abnormal dreams
Constipation
Headache (pain in head)
Parkinson's disease
Fall
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anaemia (lack of blood)

What are the common drug interactions of Renvela and Fenofibrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abnormal dreams
Constipation
Headache (pain in head)
Chronic kidney disease
Renal failure (kidney dysfunction)
Insomnia (sleeplessness)
Tooth extraction

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal injury (kidney injury)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Blood creatinine increased
Emotional distress

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Emotional distress
Impaired work ability
Pain

60+:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Death
Blood pressure decreased
Dizziness
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 34.43%
High Blood Pressure: 12 people, 19.67%
Depression: 10 people, 16.39%
Pain: 9 people, 14.75%
Gout (uric acid crystals building up in the body): 9 people, 14.75%
Diabetes: 9 people, 14.75%
Cardiac Disorder: 9 people, 14.75%
Hyperkalemia (damage to or disease of the kidney): 7 people, 11.48%
Stable Angina (a constant chest pain): 6 people, 9.84%
Neuropathy Peripheral (surface nerve damage): 6 people, 9.84%

* Approximation only. Some reports may have incomplete information.

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