Piperacillin and Methyldopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Piperacillin (piperacillin sodium) and Methyldopa (methyldopa). Common drug interactions include dyspnoea among females and bronchopulmonary aspergillosis among males.

The phase IV clinical study analyzes what interactions people have when they take Piperacillin and Methyldopa. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Piperacillin?

Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

On Aug, 06, 2026

39 people who take Piperacillin and Methyldopa together, and have interactions are studied.

Piperacillin and Methyldopa drug interactions.

What are the common drug interactions of Piperacillin and Methyldopa, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Oliguria (not enough urine)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Vaginal haemorrhage (vaginal bleeding)
Blood creatine increased
Premature baby
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Chronic kidney disease
Maternal exposure during pregnancy (use of substance during pregnancy)

male:

Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Drug ineffective
Erectile dysfunction
Haemoglobinaemia (excess of haemoglobin in the blood plasma)
Drug hypersensitivity

What are the common drug interactions of Piperacillin and Methyldopa, by age (0-1 to 60+)? *:

0-1:

Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Haemoglobinaemia (excess of haemoglobin in the blood plasma)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

2-9:

n/a

10-19:

n/a

20-29:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

30-39:

Tachypnoea (a condition of rapid breathing over 20 per minute)
Vaginal haemorrhage (vaginal bleeding)
Blood creatine increased
Maternal exposure during pregnancy (use of substance during pregnancy)
Blood creatinine increased
Pregnancy
Drug ineffective
Abdominal pain lower
Chest pain
Dyspnoea (difficult or laboured respiration)

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

n/a

60+:

Drug hypersensitivity

What are the existing conditions these people have? *

Maternal Therapy To Enhance Foetal Lung Maturity: 18 people, 46.15%
Upper Respiratory Tract Infection: 11 people, 28.21%
Pain: 5 people, 12.82%
Immature Respiratory System: 5 people, 12.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.69%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 7.69%
Bone Marrow Conditioning Regimen: 3 people, 7.69%
Sinusitis (inflammation of sinus): 2 people, 5.13%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 5.13%
Leukopenia (less number of white blood cells in blood): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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