Syeda and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Syeda (drospirenone; ethinyl estradiol) and Metformin (metformin hydrochloride). Common drug interactions include diarrhoea among females.

The phase IV clinical study analyzes what interactions people have when they take Syeda and Metformin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Syeda?

Syeda has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 218 Syeda users. Check the latest studies of Syeda.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,355 Metformin users. Check the latest studies of Metformin.

On Aug, 06, 2026

11 people who take Syeda and Metformin together, and have interactions are studied.

What are the common drug interactions of Syeda and Metformin, by gender? *:

female:

Diarrhoea
Dizziness
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Gastric ulcer (stomach ulcer)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Headache (pain in head)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatomegaly (abnormal enlargement of the liver)

male:

n/a

What are the common drug interactions of Syeda and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Psoriasis (immune-mediated disease that affects the skin)

20-29:

Chest discomfort
Chest pain
Dyspnoea (difficult or laboured respiration)
Exercise tolerance decreased
Muscular weakness (muscle weakness)
Psoriasis (immune-mediated disease that affects the skin)

30-39:

Aphasia (damage to the parts of the brain that control language)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Dyspnoea (difficult or laboured respiration)
Fall
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Hypophagia (reduced food intake)
Malaise (a feeling of general discomfort or uneasiness)

40-49:

Abdominal discomfort
Abdominal distension
Fatigue (feeling of tiredness)
Gastric ulcer (stomach ulcer)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Headache (pain in head)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatomegaly (abnormal enlargement of the liver)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 5 people, 45.45%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 36.36%
Type 2 Diabetes: 1 person, 9.09%
Hypokalemia (low potassium): 1 person, 9.09%
Headache (pain in head): 1 person, 9.09%
Chronic Respiratory Failure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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