Plan b one-step and Yaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plan b one-step (levonorgestrel) and Yaz (drospirenone; ethinyl estradiol). Common drug interactions include menstruation irregular among females.

The phase IV clinical study analyzes what interactions people have when they take Plan b one-step and Yaz. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Plan b one-step?

Plan b one-step has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 36,276 Plan b one-step users. Check the latest studies of Plan b one-step.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

On Jul, 14, 2026

55 people who take Plan b one-step and Yaz together, and have interactions are studied.

Plan b one-step and Yaz drug interactions.

What are the common drug interactions of Plan B One-Step and Yaz, by gender? *:

female:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Vomiting
Abdominal pain lower
Anxiety
Abdominal pain upper
Gallbladder disorder
Abdominal distension

male:

n/a

What are the common drug interactions of Plan B One-Step and Yaz, by age (0-1 to 60+)? *:

0-1:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Underweight

2-9:

n/a

10-19:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Menstruation irregular
Abdominal pain lower
Dizziness
Vomiting
Anxiety
Dyspareunia (painful sexual intercourse)

20-29:

Menstruation irregular
Injury
Nausea (feeling of having an urge to vomit)
Pain
Dizziness
Headache (pain in head)
Cholecystitis chronic (long lasting infection of gallbladder)
Diarrhoea
Fatigue (feeling of tiredness)
Abdominal pain lower

30-39:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Abdominal distension
Abdominal pain
Abdominal pain upper
Anaemia (lack of blood)
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Dizziness

40-49:

n/a

50-59:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Gallbladder disorder
Injury
Muscle spasms (muscle contraction)
Pain

60+:

n/a

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 5.45%
Pain: 3 people, 5.45%
Menstruation Irregular: 3 people, 5.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.45%
Depression: 3 people, 5.45%
Acne (skin problems that cause pimples): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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